Evidence map›Paper›PMID 29380360›Full record

ArticleChild development2018

Dorsomedial Prefrontal Activity to Sadness Predicts Later Emotion Suppression and Depression Severity in Adolescent Girls.

Veronika Vilgis, Kristina L Gelardi, Jonathan L Helm, Erika E Forbes, Alison E Hipwell, Kate Keenan, Amanda E Guyer

Abstract read
In one paragraph

Article in Child development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Adolescent Externalizing Problems: Contributions of Community Crime Exposure and Neural Function During Emotion Introspection in Mexican-Origin Youth.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Veronika VilgisUniversity of California, Davis.
Kristina L GelardiUniversity of California, Davis.
Jonathan L HelmSan Diego State University.
Erika E ForbesUniversity of Pittsburgh.
Alison E HipwellUniversity of Pittsburgh.
Kate KeenanUniversity of Chicago.
Amanda E GuyerUniversity of California, Davis.

Funding

The Development of Conduct Disorder in GirlsR01MH056630 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOEBER, ROLF · 1998 to 2012
$18.9M
Development of Anhedonia in High-Risk AdolescentsR01MH104418 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FORBES, ERIKA E · 2015 to 2020
$3.1M
Changes in brain function during adolescence and risk for depression in girlsR01MH093605 · NIMH · UNIVERSITY OF CHICAGO · PI FORBES, ERIKA E, GUYER, AMANDA E · 2011 to 2015
$2.9M
Preadolescent Precursors to Depression in GirlsR01MH066167 · NIMH · UNIVERSITY OF CHICAGO · PI KEENAN, KATHRYN ELIZABETH · 2004 to 2008
$2.6M
NIMH NIH HHS R01 MH056630NIMH NIH HHS R01 MH066167NIMH NIH HHS R01 MH093605NIMH NIH HHS R01 MH104418
6 · The paper itself

Abstract

The present study used cross-lagged panel analyses to test longitudinal associations among emotion regulation, prefrontal cortex (PFC) function, and depression severity in adolescent girls. The ventromedial and dorsomedial PFC (vmPFC and dmPFC) were regions of interest given their roles in depression pathophysiology, self-referential processing, and emotion regulation. At ages 16 and 17, seventy-eight girls completed a neuroimaging scan to assess changes in vmPFC and dmPFC activation to sad faces, and measures of depressive symptom severity and emotion regulation. The 1-year cross-lagged effects of dmPFC activity at age 16 on expressive suppression at age 17 and depressive symptomatology at age 17 were significant, demonstrating a predictive relation between dmPFC activity and both suppression and depressive severity.

Indexed as

Severity of Illness IndexAdolescentAdolescent BehaviorAffective SymptomsBrain MappingDepressionFemaleFollow-Up StudiesHumansMagnetic Resonance ImagingPrefrontal CortexSadness

Identifiers

PMID29380360
PMCPMC5948133

What Socratic holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.