Evidence map›Paper›PMID 29382900›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2018

Seasonal variation in nocturnal home blood pressure fall: the Nagahama study.

Yasuharu Tabara, Takeshi Matsumoto, Kimihiko Murase, Shunsuke Nagashima, Toyohiro Hirai, Shinji Kosugi, Takeo Nakayama, Tomoko Wakamura, Kazuo Chin, Fumihiko Matsuda and 1 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07606859 (Innovative Solutions Across the MEDiterranean for Mitigation of Climate Change-related heaLth rIsks and Enhancing Health systeM Resilience), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07606859 narecruitingnot on this mapstarted 2026, after this paper: background citation

Innovative Solutions Across the MEDiterranean for Mitigation of Climate Change-related heaLth rIsks and Enhancing Health systeM Resilience

TypeinterventionalSponsorUniversity of CyprusRan2026 to 2027Enrolled102ConditionsHypertension Arterial, 65 Years OlderArmsHeat intervention, Heat and air pollution mitigation intervention
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. The Japanese Society of Hypertension Practical Consensus Guidelines for Seasonal Blood Pressure Management.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  3. Review
  4. Intraindividual correlations between nocturnal urination frequency and sleep blood pressure: the Nagahama Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  5. Does self-measurement of sleep blood pressure at home exert a favorable effect on blood pressure control?Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  6. Article
  7. Seasonal variation in blood pressure and its impact on target organ damage and cardiovascular disease incidence.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
    Article
  8. Seasonal variation in blood pressure: current evidence and recommendations for hypertension management.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
    Review
  9. Nighttime home blood pressure as a mediator of N-terminal pro-brain natriuretic peptide in cardiovascular events.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
    Article
  10. The relationship between home blood pressure measurement and room temperature in a Japanese general population.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Characteristics of visit-to-visit blood pressure variability in hemodialysis patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yasuharu TabaraCenter for Genomic Medicine, Graduate School of Medicine Kyoto University, Kyoto, Japan. tabara@genome.med.kyoto-u.ac.jp.
Takeshi MatsumotoDepartment of Respiratory Medicine, Graduate School of Medicine Kyoto University, Kyoto, Japan.
Kimihiko MuraseDepartment of Respiratory Care and Sleep Control Medicine, Graduate School of Medicine Kyoto University, Kyoto, Japan.
Shunsuke NagashimaDepartment of Human Health Science, Graduate School of Medicine Kyoto University, Kyoto, Japan.
Toyohiro HiraiDepartment of Respiratory Medicine, Graduate School of Medicine Kyoto University, Kyoto, Japan.
Shinji KosugiDepartment of Medical Ethics and Medical Genetics, Kyoto University School of Public Health, Kyoto, Japan.
Takeo NakayamaDepartment of Health Informatics, Kyoto University School of Public Health, Kyoto, Japan.
Tomoko WakamuraDepartment of Human Health Science, Graduate School of Medicine Kyoto University, Kyoto, Japan.
Kazuo ChinDepartment of Respiratory Care and Sleep Control Medicine, Graduate School of Medicine Kyoto University, Kyoto, Japan.
Fumihiko MatsudaCenter for Genomic Medicine, Graduate School of Medicine Kyoto University, Kyoto, Japan.
and the Nagahama study group
Kyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormalities in circadian blood pressure (BP) variation have been suggested to be associated with cardiovascular diseases and mortality. Factors affecting this variability need to be clarified to precisely evaluate the risk of circadian BP abnormalities. Given the seasonal differences in casual BP, it was hypothesized that nocturnal BP may also differ by season. Here, we aimed to clarify the seasonality of circadian BP variation, as well as the factors associated with this seasonality, in a large-scale general population (n = 4780). This is a cross-sectional study based on multiday BP values measured in the evening, during sleep, and in the morning. Measurements were taken at home using an automatic cuff-oscillometric device. The sleeping period was objectively defined by actigraphy. The nocturnal systolic BP fall was significantly less in individuals whose BP was measured during the summer season (summer, -5.8 ± 7.8%; middle (spring or autumn), -8.2 ± 7.5%; winter, -11.0 ± 7.7%; p < 0.001), resulting in higher frequencies of riser (summer, 19.9; middle, 12.8; winter, 7.8%) and non-dipper (summer, 51.4; middle, 46.3; winter, 37.0%) patterns in the summer season (p < 0.001). The results of linear regression analysis identified the middle (β = 0.154, p < 0.001) and summer season (β = 0.261, p < 0.001) as strong positive determinants for decreasing the nocturnal SBP fall. No seasonality was observed in day-to-day variability of the dipping pattern (Kendall's coefficient: winter, 0.527; middle, 0.539; summer, 0.515). The nocturnal BP fall was largely different by season, with a higher frequency of riser and non-dipper patterns in the summer. The seasonality might not be due to the seasonal difference in day-to-day variability of nocturnal BP changes.

Indexed as

SeasonsActigraphyAdultAgedBlood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmCohort StudiesCross-Sectional StudiesFemaleHumansHypertensionJapanMaleMiddle AgedProspective Studies

Identifiers

PMID29382900
OpenAlexW2797693546

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.