Evidence map›Paper›PMID 29399328›Full record

ReviewF1000Research2018

JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders.

William Vainchenker, Emilie Leroy, Laure Gilles, Caroline Marty, Isabelle Plo, Stefan N Constantinescu

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 155 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Targeting DESI2 as a Novel Therapeutic Strategy for JAK2-Mutant Leukemias.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  8. Article
  9. Observational
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Pyrimidine compounds BY4003 and BY4008 inhibit glioblastoma cells growth via modulating JAK3/STAT3 signaling pathway.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Article
  17. Article
  18. Review
  19. Review
  20. Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

William VainchenkerINSERM UMR 1170, Gustave Roussy, Villejuif, France.ORCID https://orcid.org/0000-0003-4705-202X
Emilie LeroySignal Transduction & Molecular Hematology Unit, Ludwig Institute for Cancer Research, Brussels, Belgium.
Laure GillesInstitut National de la Transfusion Sanguine, Paris, France.
Caroline MartyINSERM UMR 1170, Gustave Roussy, Villejuif, France.
Isabelle PloINSERM UMR 1170, Gustave Roussy, Villejuif, France.
Stefan N ConstantinescuSignal Transduction & Molecular Hematology Unit, Ludwig Institute for Cancer Research, Brussels, Belgium.
Inserm · FRLudwig Cancer Research · BEInstitut National de la Transfusion Sanguine · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

JAK inhibitors have been developed following the discovery of the

Indexed as

allosteric inhibitorauto-immune diseasesinflammationJAK inhibitorsMPN

Identifiers

PMID29399328
PMCPMC5773931
OpenAlexW2783739433

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.