ArticleBMC veterinary research2018
Molecular analysis of carnivore Protoparvovirus detected in white blood cells of naturally infected cats.
Article in BMC veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Molecular Detection and Phylogenetic Characterization of CPV-2c in Apparently Healthy Domestic Cats in the Guadalajara Metropolitan Area, Mexico.Veterinary sciences · 2026Article
- Molecular detection of vector-borne and hemotropic pathogens in raccoons (International journal for parasitology. Parasites and wildlife · 2026Review
- Feline panleukopenia virus and canine parvovirus: development of two qPCR assays with high-resolution melting analysis and molecular epidemiology in dogs and cats from Northen Italy in 2017-2023.Frontiers in veterinary science · 2026Article
- Molecular Epidemiology of Highly Diffusive DNA Viruses in Dogs and Cats from Romania.Animals : an open access journal from MDPI · 2025Article
- Red Foxes (Microorganisms · 2025Article
- Emergence, surge, and fading of the novel feline parvovirus Thr390Ala mutant in Egyptian cats during 2023: insights from a comprehensive full-length VP2 genetic analysis.BMC veterinary research · 2025Article
- Comparative Detection and Genetic Characterization of Feline Panleukopenia Virus in Bangladesh.Veterinary medicine and science · 2025Article
- Viral metagenomics reveals parvovirus dark matter of herbivorous wildlife from the Qinghai-Tibet Plateau.BMC microbiology · 2025Article
- Investigation of canine parvovirus occurrence in cats with clinical signs of feline panleukopenia in Slovakia - pilot study.Journal of veterinary research · 2024Article
- Low Intrahost and Interhost Genetic Diversity ofViruses · 2022Article
- Molecular characteristics and genetic evolutionary analyses of circulating parvoviruses derived from cats in Beijing.BMC veterinary research · 2022Article
- Canine circovirus and Canine adenovirus type 1 and 2 in dogs with parvoviral enteritis.Veterinary research communications · 2022Article
- Molecular characterization ofFrontiers in veterinary science · 2022Article
- Integrated Use of Molecular Techniques to Detect and Genetically Characterise DNA Viruses in Italian Wolves (Animals : an open access journal from MDPI · 2021Article
- Emerging Parvoviruses in Domestic Cats.Viruses · 2021Review
- Molecular survey of parvovirus, astrovirus, coronavirus, and calicivirus in symptomatic dogs.Veterinary research communications · 2021Article
- Virome of a Feline Outbreak of Diarrhea and Vomiting Includes Bocaviruses and a Novel Chapparvovirus.Viruses · 2020Article
- Feline Parvovirus Seroprevalence Is High in Domestic Cats from Disease Outbreak and Non-Outbreak Regions in Australia.Viruses · 2020Article
- Limited Intrahost Diversity and Background Evolution Accompany 40 Years of Canine Parvovirus Host Adaptation and Spread.Journal of virology · 2019Article
- Development and application of a multiplex PCR method for the simultaneous detection and differentiation of feline panleukopenia virus, feline bocavirus, and feline astrovirus.Archives of virology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCats are susceptible to feline panleukopenia virus (FPV) and canine parvovirus (CPV) variants 2a, 2b and 2c. Detection of FPV and CPV variants in apparently healthy cats and their persistence in white blood cells (WBC) and other tissues when neutralising antibodies are simultaneously present, suggest that parvovirus may persist long-term in the tissues of cats post-infection without causing clinical signs. The aim of this study was to screen a population of 54 cats from Sardinia (Italy) for the presence of both FPV and CPV DNA within buffy coat samples using polymerase chain reaction (PCR). The DNA viral load, genetic diversity, phylogeny and antibody titres against parvoviruses were investigated in the positive cats.
resultsCarnivore protoparvovirus 1 DNA was detected in nine cats (16.7%). Viral DNA was reassembled to FPV in four cats and to CPV (CPV-2b and 2c) in four cats; one subject showed an unusually high genetic complexity with mixed infection involving FPV and CPV-2c. Antibodies against parvovirus were detected in all subjects which tested positive to DNA parvoviruses.
conclusionsThe identification of FPV and CPV DNA in the WBC of asymptomatic cats, despite the presence of specific antibodies against parvoviruses, and the high genetic heterogeneity detected in one sample, confirmed the relevant epidemiological role of cats in parvovirus infection.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.