ReviewClinics in perinatology2018
Neonatal Cushing Syndrome: A Rare but Potentially Devastating Disease.
Review in Clinics in perinatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Three cases of pediatric adrenocortical carcinoma with intermediate malignant potential: a case report with literature review.AME case reports · 2026Article
- Paediatric Cushing syndrome: a prospective, multisite, observational cohort study.The Lancet. Child & adolescent health · 2024Observational
- The longest reported survival of a child with McCune-Albright syndrome and a severe early presenting phenotype consisting of neonatal cushing syndrome, cardiac and liver diseases.Journal of surgical case reports · 2023Article
- An update on, and genetics of refractory adenomas of childhood.Pituitary · 2023Review
- Adrenal Cushing's syndrome in children.Frontiers in endocrinology · 2023Review
- Review
- Photographic Journey of Cushing Syndrome.Indian journal of pediatrics · 2021Article
- Neonatal Cushing Syndrome.Indian journal of pediatrics · 2021Article
- Aggressive pituitary tumors in the young and elderly.Reviews in endocrine & metabolic disorders · 2020Review
- Fibrous Dysplasia/McCune-Albright Syndrome: A Rare, Mosaic Disease of Gα s Activation.Endocrine reviews · 2020Review
- Cushing syndrome: Old and new genes.Best practice & research. Clinical endocrinology & metabolism · 2020Review
- The Genetics of Pituitary Adenomas.Journal of clinical medicine · 2019Review
- Neonatal McCune-Albright Syndrome: A Unique Syndromic Profile With an Unfavorable Outcome.JBMR plus · 2019Article
- The Clinical Spectrum of McCune-Albright Syndrome and Its Management.Hormone research in paediatrics · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Neonatal Cushing syndrome (CS) is most commonly caused by exogenous administration of glucocorticoids and rarely by endogenous hypercortisolemia. CS owing to adrenal lesions is the most common cause of endogenous CS in neonates and infants, and adrenocortical tumors (ACTs) represent most cases. Many ACTs develop in the context of a TP53 gene mutation, which causes Li-Fraumeni syndrome. More rarely, neonatal CS presents as part of other syndromes such as McCune-Albright syndrome or Beckwith-Wiedemann syndrome. Management usually includes resection of the primary tumor with or without additional medical treatment, but manifestations may persist after resolution of hypercortisolemia.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.