ArticleExperimental neurology2018
Dissipation of transmembrane potassium gradient is the main cause of cerebral ischemia-induced depolarization in astrocytes and neurons.
Abstract read
In one paragraph
Article in Experimental neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 35 citations in OpenAlex.
- Subarachnoid hemorrhage mediates human neocortical network, membrane potential, and action potential bursting via glutamate receptors.Communications biology · 2025Article
- Interplay Among Synaptic Glutamate Release and Excitotoxicity: Neuronal Damage and Graphene-Based Materials Related Protection.Life (Basel, Switzerland) · 2025Review
- Intravenous AAV9-Science advances · 2025Article
- Enhanced Response of ZnO Nanorod-Based Flexible MEAs for Recording Ischemia-Induced Neural Activity in Acute Brain Slices.Nanomaterials (Basel, Switzerland) · 2025Article
- A dangerous liaison: Spreading depolarization and tissue acidification in cerebral ischemia.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025Review
- An Empirical-Theoretical Approach to Determine Astroglial Potassium Upon Ischemic Stress.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Aquaporins: Gatekeepers of Fluid Dynamics in Traumatic Brain Injury.International journal of molecular sciences · 2024Review
- GLT-1a glutamate transporter nanocluster localization is associated with astrocytic actin and neuronal Kv2 clusters at sites of neuron-astrocyte contact.Frontiers in cell and developmental biology · 2024Article
- ALS-like pathology diminishes swelling of spinal astrocytes in the SOD1 animal model.Frontiers in cellular neuroscience · 2024Article
- The deletion of AQP4 and TRPV4 affects astrocyte swelling/volume recovery in response to ischemia-mimicking pathologies.Frontiers in cellular neuroscience · 2024Article
- Article
- Chronic Stress Impairs the Structure and Function of Astrocyte Networks in an Animal Model of Depression.Neurochemical research · 2023Article
- Glioma epileptiform activity and progression are driven by IGSF3-mediated potassium dysregulation.Neuron · 2023Article
- Microglia maintain the normal structure and function of the hippocampal astrocyte network.Glia · 2022Article
- Changes in Astroglial KInternational journal of molecular sciences · 2022Article
- On the electrical passivity of astrocyte potassium conductance.Journal of neurophysiology · 2021Review
- Dysregulation of Astrocyte Ion Homeostasis and Its Relevance for Stroke-Induced Brain Damage.International journal of molecular sciences · 2021Review
- Occlusion of activity dependent synaptic plasticity by late hypoxic long term potentiation after neonatal intermittent hypoxia.Experimental neurology · 2021Review
- Article
- Epileptiform Neuronal Discharges Impair Astrocyte Syncytial Isopotentiality in Acute Hippocampal Slices.Brain sciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Yixing DuDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Wei WangDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA; Department of Physiology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan 430030, China.
Anthony D LuttonTrace Element Research Laboratory, The Ohio State University, Columbus, OH 43210, USA.
Conrad M KiyoshiDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Baofeng MaDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Anne T TaylorDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
John W OlesikTrace Element Research Laboratory, The Ohio State University, Columbus, OH 43210, USA.
Dana M McTigueDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Candice C AskwithDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Min ZhouDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. Electronic address: zhou.787@osu.edu.
The Ohio State University Wexner Medical Center · USThe Ohio State University · US
Funding
Ohio State University Neuroscience Center Core-Core EP30NS104177 · NINDS · OHIO STATE UNIVERSITY · PI BROWN, ANTHONY · 2017 to 2020
$1.9MRestoring Iron Homeostasis to Promote Recovery after Spinal Cord InjuryR01NS082095 · NINDS · OHIO STATE UNIVERSITY · PI MCTIGUE, DANA M · 2013 to 2017
$1.8MInvolvement of astrocytic two-pore domain K+ channels in ischemic pathologyR01NS062784 · NINDS · ORDWAY RESEARCH INSTITUTE, INC. · PI ZHOU, MIN · 2010 to 2014
$1.7MAstrocyte function at syncytial system levelsR56NS097672 · NINDS · OHIO STATE UNIVERSITY · PI ZHOU, MIN · 2016 to 2016
$385kNINDS NIH HHS P30 NS104177NINDS NIH HHS R01 NS062784NINDS NIH HHS R01 NS082095NINDS NIH HHS R56 NS097672
Abstract
Membrane potential (V
Indexed as
AnimalsAnimals, NewbornAntigensAstrocytesBiophysical PhenomenaChondroitin Sulfate Proteoglycan 4Electric ConductivityFemaleGiant CellsGlucoseHippocampusHypoxiaMaleMembrane PotentialsMiceMice, Inbred C57BLAntigensChondroitin Sulfate Proteoglycan 4GlucoseOxygenPotassiumProteoglycansReceptor, Platelet-Derived Growth Factor alphaAstrocytesBrain ischemiaIon channelNeuronsNG2 glia
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.