Evidence map›Paper›PMID 29413863›Full record

ArticleBioelectrochemistry (Amsterdam, Netherlands)2018

Electropermeabilization of cells by closely spaced paired nanosecond-range pulses.

Iurii Semenov, Maura Casciola, Bennet L Ibey, Shu Xiao, Andrei G Pakhomov

Abstract read
In one paragraph

Article in Bioelectrochemistry (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  9. Review
  10. Review
  11. Article
  12. Article
  13. Excitation and electroporation by MHz bursts of nanosecond stimuli.Biochemical and biophysical research communications · 2019
    Article
  14. Excitation of murine cardiac myocytes by nanosecond pulsed electric field.Journal of cardiovascular electrophysiology · 2019
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Iurii SemenovFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA.
Maura CasciolaFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA.
Bennet L IbeyRadio Frequency Bioeffects Branch, Air Force Research Laboratories, Ft. Sam Houston, San Antonio, TX, USA.
Shu XiaoFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA; Department of Electrical and Computer Engineering, Old Dominion University, Norfolk, VA 23508, USA.
Andrei G PakhomovFrank Reidy Research Center for Bioelectrics, Old Dominion University, Norfolk, VA 23508, USA. Electronic address: 2andrei@pakhomov.net.
Old Dominion University · USUnited States Air Force Research Laboratory · US

Funding

Low Energy Defibrillation with Nanosecond Pulsed Electric FieldR01HL128381 · NHLBI · OLD DOMINION UNIVERSITY · PI PAKHOMOV, ANDREI G · 2015 to 2018
$1.5M
NHLBI NIH HHS R01 HL128381
6 · The paper itself

Abstract

Decreasing the time gap between two identical electric pulses is expected to render bioeffects similar to those of a single pulse of equivalent total duration. In this study, we show that it is not necessarily true, and that the effects vary for different permeabilization markers. We exposed individual CHO or NG108 cells to one 300-ns pulse (3.7-11.6 kV/cm), or a pair of such pulses (0.4-1000 μs interval), or to a single 600-ns pulse of the same amplitude. Electropermeabilization was evaluated (a) by the uptake of YO-PRO-1 (YP) dye; (b) by the amplitude of elicited Ca

Indexed as

Cell Membrane PermeabilityAnimalsBenzoxazolesCalciumCell Line, TumorCHO CellsCricetulusDrug Delivery SystemsElectroporationFluorescent DyesQuinolinium CompoundsRatsThalliumBenzoxazolesCalciumFluorescent DyesQuinolinium CompoundsThalliumYO-PRO 1ElectropermeabilizationElectroporationMembrane permeabilityNanoporesNanosecond pulses

Identifiers

PMID29413863
PMCPMC5907791
OpenAlexW2791209983

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.