Evidence mapPaperPMID 29417249Full record

ReviewEuropean radiology2018

Post-contrast acute kidney injury. Part 2: risk stratification, role of hydration and other prophylactic measures, patients taking metformin and chronic dialysis patients : Recommendations for updated ESUR Contrast Medium Safety Committee guidelines.

Aart J van der Molen, Peter Reimer, Ilona A Dekkers, Georg Bongartz, Marie-France Bellin, Michele Bertolotto, Olivier Clement, Gertraud Heinz-Peer, Fulvio Stacul, Judith A W Webb and 1 more

2 registry-linked trialsOpen access · hybridAbstract readReview
In one paragraph

Review in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 125 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 14 pooled it
21.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06139952 phase4completedstarted 2023, after this paper: background citation

Assessment of the Effect of Atorvastatin and N-acetyl Cysteine on Prevention of Contrast Induced Nephropathy in Patients Undergoing Coronary Angiography CIN

Ran2023Enrolled120Registered outcomes2Posted comparisons0ConditionsCoronary Artery Disease, Nephropathy; Toxic, DrugsArmsAtorvastatin 80mg, N-acetyl cysteine, Normal Saline
Open the trial in the graph
NCT05283512 narecruitingnot on this mapstarted 2022, after this paper: background citation

Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease (ENRICH): A Randomized Controlled Trial

TypeinterventionalSponsorOdense University HospitalRan2022 to 2027Enrolled254ConditionsContrast-induced Nephropathy, Kidney Injury, Kidney Failure, Chronic, Risk ReductionArmsPreventive treatment with IV-hydration, Preventive treatment with oral hydration
3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 14 syntheses or guidelines pooled it, 275 citations in OpenAlex.

  1. Safety and evidence of COEuropean radiology · 2025
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  5. CIRSE Standards of Practice on Carotid Artery Stenting.Cardiovascular and interventional radiology · 2024
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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 8 countries.

Aart J van der MolenDepartment of Radiology, C2-S, Leiden University Medical Center, Albinusdreef 2, NL-2333 ZA, Leiden, The Netherlands.
Peter ReimerInstitute for Diagnostic and Interventional Radiology Klinikum Karlsruhe, Moltkestraße 90, D-76133, Karlsruhe, Germany.
Ilona A DekkersDepartment of Radiology, C2-S, Leiden University Medical Center, Albinusdreef 2, NL-2333 ZA, Leiden, The Netherlands.
Georg BongartzDepartment of Diagnostic Radiology, University Hospitals of Basel, Petersgaben 4, CH-4033, Basel, Switzerland.
Marie-France BellinService Central de Radiologie Hôpital Paul Brousse 14, av. P.-V.-Couturier, F-94807, Villejuif, France.
Michele BertolottoDepartment of Radiology, University of Trieste, Strada di Fiume 447, I-34149, Trieste, Italy.
Olivier ClementDepartment of Radiology, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, 20 rue Leblanc, Paris Cedex 15, F-71015, Paris, France.
Gertraud Heinz-PeerDepartment of Radiology, Zentralinstitut für medizinische Radiologie, Diagnostik und Intervention, Landesklinikum St. Pölten, Propst Führer-Straße 4, AT-3100, St. Pölten, Austria.
Fulvio StaculS.C. Radiologia Ospedale Maggiore, Piazza Ospitale 1, I-34129, Trieste, Italy.
Judith A W WebbDepartment of Radiology, St. Bartholomew's Hospital, University of London, West Smithfield, EC1A 7BE, London, UK.
Henrik S ThomsenDepartment of Diagnostic Radiology 54E2, Copenhagen University Hospital Herlev, Herlev Ringvej 75, DK-2730, Herlev, Denmark. Henrik.Thomsen@regionh.dk.
Leiden University Medical Center · NLAssistance Publique – Hôpitaux de Paris · FRCopenhagen University Hospital · DKHôpital Paul-Brousse · FROspedale Maggiore · ITStädtisches Klinikum Karlsruhe · DESt Bartholomew's Hospital · GBUniversitätsklinikum St. Pölten · ATUniversity Hospital of Basel · CHUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe Contrast Media Safety Committee (CMSC) of the European Society of Urogenital Radiology (ESUR) has updated its 2011 guidelines on the prevention of post-contrast acute kidney injury (PC-AKI). The results of the literature review and the recommendations based on it, which were used to prepare the new guidelines, are presented in two papers. AREAS COVERED IN PART 2: Topics reviewed include stratification of PC-AKI risk, the need to withdraw nephrotoxic medication, PC-AKI prophylaxis with hydration or drugs, the use of metformin in diabetic patients receiving contrast medium and the need to alter dialysis schedules in patients receiving contrast medium. KEY POINTS: • In CKD, hydration reduces the PC-AKI risk • Intravenous normal saline and intravenous sodium bicarbonate provide equally effective prophylaxis • No drugs have been consistently shown to reduce the risk of PC-AKI • Stop metformin from the time of contrast medium administration if eGFR < 30 ml/min/1.73 m

Indexed as

Renal DialysisAcute Kidney InjuryAdultChildContraindications, DrugContrast MediaDrug SubstitutionFemaleFluid TherapyGlomerular Filtration RateHumansHypoglycemic AgentsInjections, Intra-ArterialIodineMaleMetforminContrast MediaHypoglycemic AgentsIodineMetforminSodium ChlorideAcute kidney injuryContrast mediaHaemodialysisMetforminPractice guidelines

Identifiers

PMID29417249
PMCPMC5986837
OpenAlexW2786550682

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.