Evidence map›Paper›PMID 29419785›Full record

Trial reportNutrients2018

Macronutrient Composition and Food Form Affect Glucose and Insulin Responses in Humans.

Shila Shafaeizadeh, Leilani Muhardi, Christiani Jeyakumar Henry, Bert J M van de Heijning, Eline M van der Beek

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Observational
  4. Personalized glucose prediction usingFrontiers in nutrition · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Shila ShafaeizadehNutricia Research, Matrix Building #05-01b, 30 Biopolis Street, Singapore 138671, Singapore. shila.shafaeizadeh@danone.com.
Leilani MuhardiDanone Early Life Nutrition, Cyber 2 Tower, 15th Floor, Jl. HR. Rasuna Said #X-5 No. 13, South Jakarta 12950, Indonesia. Muhardi@danone.com.
Christiani Jeyakumar HenryClinical Nutrition Research Centre (CNRC), Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), and National University Health System, Centre for Translational Medicine, 14 Medical Drive #07-02, MD 6 Building, Yong Loo Lin School of Medicine, Singapore 117599, Singapore. Jeya_Henry@sics.a-star.edu.sg.ORCID 0000-0002-1602-0140
Bert J M van de HeijningNutricia Research, Uppsalalaan 12, 3584 CT Utrecht, The Netherlands. Bert.vandeheijning@danone.com.
Eline M van der BeekNutricia Research, Uppsalalaan 12, 3584 CT Utrecht, The Netherlands. Eline.vanderbeek@danone.com.
Agency for Science, Technology and Research · SGNutricia Research (Netherlands) · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycaemic index (GI) is used as an indicator to guide consumers in making healthier food choices. We compared the GI, insulin index (II), and the area under the curve for blood glucose and insulin as glucose (GR) and insulin responses (IR) of a newly developed liquid nutritional formula with one commercially available liquid product with different types of carbohydrates. We then evaluated the glucose and insulin responses of two test foods with comparable energy density and protein percentage but presented in different food forms (liquid vs. solid). Fourteen healthy women participated in the study. GI, II, GR, and IR were assessed after (independent) consumption of two liquid products and a solid breakfast meal. The two liquid foods showed comparable GI, whilst the liquid form appeared to produce lower median GI (25 vs. 54), and II (52 vs. 98) values compared to the solid breakfast (

Indexed as

BeveragesFood, FormulatedGlycemic IndexInsulin ResistanceAdultArea Under CurveBiomarkersBlood GlucoseBreakfastCross-Over StudiesDietDietary CarbohydratesDigestionFemaleHumansHyperglycemiaBiomarkersBlood GlucoseDietary CarbohydratesInsulincarbohydrate qualityglycaemic and insulin responsesglycaemic indexinsulinemic indexnutritional formulaprotein quality

Identifiers

PMID29419785
PMCPMC5852764
OpenAlexW2793946724

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.