ArticleEvolution, medicine, and public health2017
Understanding developmental plasticity as adaptation requires an inter-generational perspective.
Article in Evolution, medicine, and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Introducing the Neuroplastic Narrative: a non-pathologizing biological foundation for trauma-informed and adverse childhood experience aware approaches.Frontiers in psychiatry · 2023Article
- Parental high-fat high-sugar diet programming and hypothalamus adipose tissue axis in male Wistar rats.European journal of nutrition · 2022Article
- Maternal internal migration and child growth and nutritional health in Peru: an analysis of the demographic and health surveys from 1991 to 2017.BMC public health · 2022Article
- A growth area: A review of the value of clinical studies of child growth for palaeopathology.Evolution, medicine, and public health · 2022Review
- Cross-Generational Effects and Non-random Developmental Response to Temperature Variation inFrontiers in cell and developmental biology · 2020Article
- Developmental plasticity as adaptation: adjusting to the external environment under the imprint of maternal capital.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
- Recent advances in understanding body weight homeostasis in humans.F1000Research · 2018Review
- Life history trade-offs and the partitioning of maternal investment: Implications for health of mothers and offspring.Evolution, medicine, and public health · 2018Review
Corrections and comments
- Commented on byResponse to Lea2017
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this issue of Evolution, Medicine and Public Health, Lea and colleagues argue that there are major advantages to bringing together biomedical and evolutionary perspectives on plasticity. To develop this approach, they propose two contrasting scenarios for 'developmental plasticity as adaptation': that it reflects adjustments to resolve the effects of early 'constraints', or that it adjusts phenotype to ecological cues in anticipation of similar conditions in adulthood. Yet neither scenario highlights the unique role of maternal phenotype, mediated by maternal investment strategy, in generating such constraints or cues. Developmental plasticity is greatest during the period when all ecological influences on the offspring are transduced by maternal phenotype. If the offspring adapts during this period, then the target of that adaptation is to maternal phenotype. Ignoring the inter-generational source of early constraints or cues prevents development of a comprehensive adaptive framework, because developmental plasticity is fundamentally relevant to the fitness of both offspring and parents.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.