ReviewEvolution, medicine, and public health2017
Developmental plasticity: Bridging research in evolution and human health.
Review in Evolution, medicine, and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed.
- Prenatal and postnatal droughts interact in shaping cognitive development.Communications medicine · 2026Article
- Accelerating discovery of cancer causes for prevention in the era of rising early-onset cancers.Cell · 2026Review
- Review
- Evolving a Field: Can Evolutionary Theory Provide What the Study of Human Evolution Requires?American journal of biological anthropology · 2025Review
- Early life functional transitions impact craniofacial morphology in osteogenesis imperfecta.Anatomical record (Hoboken, N.J. : 2007) · 2025Article
- Testing early life effects frameworks: developmental constraints and adaptive response hypotheses do not explain fertility outcomes in wild female baboons.Proceedings. Biological sciences · 2025Article
- A development-centric perspective on pace-of-life syndromes.Evolution letters · 2025Article
- The association between early-life famine exposure and adulthood risk of thyroid diseases.Frontiers in nutrition · 2025Article
- Investigating the association between season of birth and symptoms of depression and anxiety in adults.PLOS mental health · 2025Article
- Early life adversity has sex-dependent effects on survival across the lifespan in rhesus macaques.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- No relationship found between dental fluctuating asymmetry, birthweight, and birth term in two modern North American samples.American journal of human biology : the official journal of the Human Biology Council · 2024Article
- Organ transformation by environmental disruption of protein integrity and epigenetic memory in Drosophila.PLoS biology · 2024Article
- Investment by maternal grandmother buffers children against the impacts of adverse early life experiences.Scientific reports · 2024Article
- Mothers' prenatal distress accelerates adrenal pubertal development in daughters.Psychoneuroendocrinology · 2024Article
- From womb to wellness: early environmental exposures, cord blood DNA methylation and disease origins.Epigenomics · 2024Review
- Natural Animal Populations as Model Systems for Understanding Early Life Adversity Effects on Aging.Integrative and comparative biology · 2023Article
- Social and early life determinants of survival from cradle to grave: A case study in wild baboons.Neuroscience and biobehavioral reviews · 2023Review
- Conceptual and analytical approaches for modelling the developmental origins of inequality.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Early life adversity and adult social relationships have independent effects on survival in a wild primate.Science advances · 2023Article
- One genome, multiple phenotypes: decoding the evolution and mechanisms of environmentally induced developmental plasticity in insects.Biochemical Society transactions · 2023Review
Corrections and comments
- Commented on byResponse to Lea2017
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Authors and funding
4 authors.
Funding
Abstract
Early life experiences can have profound and persistent effects on traits expressed throughout the life course, with consequences for later life behavior, disease risk, and mortality rates. The shaping of later life traits by early life environments, known as 'developmental plasticity', has been well-documented in humans and non-human animals, and has consequently captured the attention of both evolutionary biologists and researchers studying human health. Importantly, the parallel significance of developmental plasticity across multiple fields presents a timely opportunity to build a comprehensive understanding of this phenomenon. We aim to facilitate this goal by highlighting key outstanding questions shared by both evolutionary and health researchers, and by identifying theory and empirical work from both research traditions that is designed to address these questions. Specifically, we focus on: (i) evolutionary explanations for developmental plasticity, (ii) the genetics of developmental plasticity and (iii) the molecular mechanisms that mediate developmental plasticity. In each section, we emphasize the conceptual gains in human health and evolutionary biology that would follow from filling current knowledge gaps using interdisciplinary approaches. We encourage researchers interested in developmental plasticity to evaluate their own work in light of research from diverse fields, with the ultimate goal of establishing a cross-disciplinary understanding of developmental plasticity.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.