Evidence mapPaperPMID 29425211Full record

ArticlePloS one2018

Effectiveness of a bioactive food compound in anthropometric measures of individuals with HIV/AIDS: A nonrandomized trial.

Rosângela Dos Santos Ferreira, Rita de Cássia Avellaneda Guimarães, Elenir Rose Jardim Cury Pontes, Lígia Aurélio Bezerra Maranhão Mendonça, Karine de Cássia Freitas, Priscila Aiko Hiane

Open access · goldAbstract readControlled Clinical Trial
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rosângela Dos Santos FerreiraNutrition Service, University Hospital, Federal University of Mato Grosso do Sul-UFMS, Campo Grande, Mato Grosso do Sul, Brazil.ORCID 0000-0001-6965-6639
Rita de Cássia Avellaneda GuimarãesPost Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul- UFMS, Campo Grande, Mato Grosso do Sul, Brazil.
Elenir Rose Jardim Cury PontesPost Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul- UFMS, Campo Grande, Mato Grosso do Sul, Brazil.
Lígia Aurélio Bezerra Maranhão MendonçaPost Graduate Program in Biotechnology, Catholic University Dom Bosco, Campo Grande, Mato Grosso do Sul, Brazil.
Karine de Cássia FreitasPost Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul- UFMS, Campo Grande, Mato Grosso do Sul, Brazil.
Priscila Aiko HianePost Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul- UFMS, Campo Grande, Mato Grosso do Sul, Brazil.
Universidade Federal de Mato Grosso do Sul · BRUniversidade Católica Dom Bosco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHighly Active Antiretroviral therapy (HAART) promotes anthropometric changes in lipid metabolism and glucose in patients with Human Immunodeficiency Virus (HIV). Functional foods play an important role on metabolism. Bioactive Food Compound (BFC) has shown effective results in changes arising from decompensated lipid metabolism due to the effects of HAART on HIV patients. From this perspective, the objective of this study is to evaluate anthropometric indicators and the body composition of patients undergoing HAART before and after consumption of BFC.

methodsThis is a prospective intervention with 180 individuals with HIV undergoing HAART. They formed two groups and were monitored for 3 months: the first group consisted of individuals who consumed BFC (n = 121) at the recommended daily intake of 40 g. The second group consisted of individuals who did not consume BFC (n = 59). We determined body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR), conicity index (CI) and antiretroviral regimen used by the patients.

resultsThe BMI among adults (p<0.001), the WC (p<0.001 and p<0.014 for men and women, respectively) and the CI (p = 0.001 and p<0.001 for men and women, respectively) increased at the end of the study in the group of individuals who did not consume BFC and remained stable in the BFC group. There were no changes in WHR in any of the groups evaluated. Regarding the antiretroviral regimens used, we observed that there was no difference between regimens as for BMI, WC, WHR and CI.

conclusionsThe BFC consumed by HIV patients undergoing HAART allowed the maintenance of anthropometric measures without increasing the mean values of conicity index, suggesting that the consumption of this bioactive compound protects the individual against the development of metabolic syndrome (MeS) in patients infected with HIV undergoing antiretroviral therapy.

Indexed as

Functional FoodAdultAgedAnthropometryAntiretroviral Therapy, Highly ActiveBody CompositionBody Mass IndexFemaleGlucoseHIV InfectionsHumansLipid MetabolismMaleMetabolic SyndromeMiddle AgedObesity, AbdominalGlucose

Identifiers

PMID29425211
PMCPMC5806863
OpenAlexW2790769099

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.