Evidence map›Paper›PMID 29429034›Full record

ArticleArchives of virology2018

Tetraspanin blockage reduces exosome-mediated HIV-1 entry.

Brian Sims, Anitra L Farrow, Sparkle D Williams, Anju Bansal, Alexandre Krendelchtchikov, Qiana L Matthews

Abstract read
In one paragraph

Article in Archives of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Roles of Exosomal Proteins: Classification, Function, and Applications.International journal of molecular sciences · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Exosome Processing and Characterization Approaches for Research and Technology Development.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  17. Review
  18. Commentary on "ExRNA · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brian SimsDivision of Neonatology, Departments of Pediatrics, Neurobiology and Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, USA.
Anitra L FarrowDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, USA.
Sparkle D WilliamsDivision of Neonatology, Departments of Pediatrics, Neurobiology and Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, USA.
Anju BansalDivision of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, USA.
Alexandre KrendelchtchikovDivision of Neonatology, Departments of Pediatrics, Neurobiology and Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, USA.
Qiana L MatthewsCenter for AIDS Research, University of Alabama at Birmingham, Birmingham, USA. qmatthews@alasu.edu.

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Aadia Rana · 1988 to 2026
$84.1M
Mentored Experiences in Research, Instruction and Teaching (MERIT) Program - administrative supplementK12GM088010 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SCHNEIDER, DAVID ALAN · 2009 to 2024
$9.2M
The Impact of Cocaine on Exosome-Mediated HIV Entry in the CNSR15DA045564 · NIDA · ALABAMA STATE UNIVERSITY · PI MATTHEWS, QIANA L · 2018 to 2018
$414k
NIDA NIH HHS R15 DA045564NIGMS NIH HHS K12 GM088010NIH HHS 5R01AI089337-04NIH HHS P30 AI027767
6 · The paper itself

Abstract

HIV-1 is one of the most studied retroviruses. The role of exosomes in HIV-1 entry and pathogenesis are beginning to be appreciated. Exosomes can incorporate host proteins that are also contained in viruses (e.g., tetraspanins).

Indexed as

Antibodies, NeutralizingCD4-Positive T-LymphocytesCell LineCulture Media, ConditionedExosomesGene ExpressionHEK293 CellsHIV-1HumansMilk, HumanMonocytesTetraspanin 28Tetraspanin 29Virus InternalizationAntibodies, NeutralizingCD81 protein, humanCD9 protein, humanCulture Media, ConditionedTetraspanin 28Tetraspanin 29

Identifiers

PMID29429034
PMCPMC5958159

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.