Evidence map›Paper›PMID 29432125›Full record

Trial reportDiabetes care2018

Clinical and Patient-Centered Outcomes in Obese Patients With Type 2 Diabetes 3 Years After Randomization to Roux-en-Y Gastric Bypass Surgery Versus Intensive Lifestyle Management: The SLIMM-T2D Study.

Donald C Simonson, Florencia Halperin, Kathleen Foster, Ashley Vernon, Allison B Goldfine

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01073020 (Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes), which is not on this map. Cited by 59 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 7 pooled it
16.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01073020 nacompletednot on this map

Surgery or Lifestyle With Intensive Medical Management in the Treatment of Type 2 Diabetes (SLIMM-T2D)

TypeinterventionalSponsorJoslin Diabetes CenterRan2010 to 2016Enrolled88ConditionsType 2 Diabetes Mellitus, ObesityArmsAllergan Adjustable Gastric Band Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group, Roux-en-Y Gastric Bypass (RYGB) Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Bypass Group
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 7 syntheses or guidelines pooled it, 134 citations in OpenAlex.

  1. Pooled it
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  8. Trial
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  12. Adjustable gastric band surgery or medical management in patients with type 2 diabetes and obesity: three-year results of a randomized trial.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019
    Trial
  13. Multidisciplinary Therapy to Target Obesity and Its Complications in Adult Population: A Narrative Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Concept analysis of diabetes-related quality of life.Health and quality of life outcomes · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Donald C SimonsonDivision of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA dsimonso@hsph.harvard.edu.ORCID 0000-0002-4670-6290
Florencia HalperinDivision of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Kathleen FosterResearch Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Ashley VernonCenter for Metabolic and Bariatric Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Allison B GoldfineResearch Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA.
Brigham and Women's Hospital · USJoslin Diabetes Center · US

Funding

Comparative Effectiveness of Medical Therapy vs. Bariatric Surgery for Obese T2DMRC1DK086918 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLDFINE, ALLISON B, LAUTZ, DAVID BRADLEY · 2009 to 2010
$1.0M
Durability and Mechanisms of Bariatric Surgery vs Medical Therapy in Obese T2DR56DK095451 · NIDDK · JOSLIN DIABETES CENTER · PI GOLDFINE, ALLISON B, LAUTZ, DAVID BRADLEY · 2012 to 2013
$277k
NIDDK NIH HHS R56 DK095451NIDDK NIH HHS RC1 DK086918
6 · The paper itself

Abstract

objectiveTo compare the effect of Roux-en-Y gastric bypass (RYGB) surgery versus intensive medical diabetes and weight management (IMWM) on clinical and patient-reported outcomes in obese patients with type 2 diabetes. RESEARCH DESIGN AND

methodsWe prospectively randomized 38 obese patients with type 2 diabetes (15 male and 23 female, with mean ± SD weight 104 ± 16 kg, BMI 36.3 ± 3.4 kg/m

resultsAfter 3 years, the RYGB group had greater weight loss (mean -24.9 kg [95% CI -29.5, -20.4] vs. -5.2 [-10.3, -0.2];

conclusionsThree years after randomization to RYGB versus IMWM, surgery produced greater weight loss, lower HbA

Indexed as

Gastric BypassRisk Reduction BehaviorAdultDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHumansHypoglycemic AgentsLife StyleMaleMiddle AgedObesityPatient-Centered CareQuality of LifeTreatment OutcomeWeight LossHypoglycemic Agents

Identifiers

PMID29432125
PMCPMC5860843
OpenAlexW2793588570

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.