Evidence map›Paper›PMID 29438986›Full record

ReviewJournal of lipid research2018

Phospholipid transfer protein: its impact on lipoprotein homeostasis and atherosclerosis.

Xian-Cheng Jiang

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Frontiers in cardiovascular medicine · 2025
    Article
  10. Review
  11. Article
  12. Review
  13. The 'omics of obesity in B-cell acute lymphoblastic leukemia.Journal of the National Cancer Institute. Monographs · 2023
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Circadian Clock Regulation on Lipid Metabolism and Metabolic Diseases.Advances in experimental medicine and biology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Xian-Cheng JiangDepartment of Cell Biology, Downstate Medical Center, State University of New York, Brooklyn, NY XJiang@downstate.edu.
State University of New York · US

Funding

Hepatic PLTP as a target for lowering LDL-cR56HL121409 · NHLBI · SUNY DOWNSTATE MEDICAL CENTER · PI JIANG, XIAN-CHENG, JIN, WEIJUN · 2014 to 2014
$400k
The Effect of SPT Deficiency on AtherosclerosisI01BX000900 · VA · VA NEW YORK HARBOR HLTHCARE/SYS/BROOKLYN · PI JIANG, XIAN-CHENG · 2012 to 2025
–
Teletechnology Accuracy for Real-time Tele-video Assessment of Physical FunctionI01RX000900 · VA · DURHAM VA MEDICAL CENTER · PI HOENIG, HELEN M. · 2015 to 2015
–
BLRD VA I01 BX000900NHLBI NIH HHS R56 HL121409RRD VA I01 RX000900
6 · The paper itself

Abstract

Phospholipid transfer protein (PLTP) is one of the major modulators of lipoprotein metabolism and atherosclerosis development in humans; however, we still do not quite understand the mechanisms. In mouse models, PLTP overexpression induces atherosclerosis, while its deficiency reduces it. Thus, mouse models were used to explore the mechanisms. In this review, I summarize the major progress made in the PLTP research field and emphasize its impact on lipoprotein metabolism and atherosclerosis, as well as its regulation.

Indexed as

HomeostasisAnimalsAtherosclerosisHumansLipoproteinsPhospholipid Transfer ProteinsLipoproteinsPhospholipid Transfer Proteinslipidslipid transfer proteinslipoproteinsphospholipid transfer proteinvery low density lipoprotein

Identifiers

PMID29438986
PMCPMC5928426
OpenAlexW2786903720

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.