Evidence map›Paper›PMID 29440033›Full record

ArticleJournal of the American Heart Association2018

Trajectories of Long-Term Normal Fasting Plasma Glucose and Risk of Coronary Heart Disease: A Prospective Cohort Study.

Zhongshang Yuan, Yang Yang, Chunxia Wang, Jing Liu, Xiubin Sun, Yi Liu, Shengxu Li, Fuzhong Xue

Abstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhongshang YuanDepartment of Epidemiology and Biostatistics, School of Public Health, Shandong University, Jinan, Shandong, China.
Yang YangDepartment of Neurology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Chunxia WangHealth Management Center, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Jing LiuDepartment of Epidemiology and Biostatistics, School of Public Health, Shandong University, Jinan, Shandong, China.
Xiubin SunDepartment of Epidemiology and Biostatistics, School of Public Health, Shandong University, Jinan, Shandong, China.
Yi LiuDepartment of Epidemiology and Biostatistics, School of Public Health, Shandong University, Jinan, Shandong, China.
Shengxu LiDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA.
Fuzhong XueDepartment of Epidemiology and Biostatistics, School of Public Health, Shandong University, Jinan, Shandong, China xuefzh@sdu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFasting plasma glucose (FPG) levels can vary over time and its longitudinal changing patterns may predict cardiometabolic risk. We aim to identify different trajectories of FPG in those who remained normoglycemic and investigate the association between trajectory groups and coronary heart disease risk in a large prospective cohort study. METHODS AND

resultsA total of 20 514 subjects between ages 20 and 80 years were included at baseline. All participants had maintained normal FPG throughout an average follow-up period of 5.8 years. We identified 3 distinct trajectories using a group-based trajectory model, labeled by initial value and changing pattern: low-increasing (n=12 694), high-increasing-decreasing (n=5330), and high-decreasing-increasing (n=2490). The coronary heart disease incidence density among these 3 groups (3.00, 4.05, and 3.26 per 1000 person-years, respectively) was significantly different (

conclusionsDistinct trajectories of long-term normal FPG are associated with the development of coronary heart disease, which is independent of other metabolic factors including FPG levels. These findings have implications for intervention and prevention of coronary heart disease among individuals who are normoglycemic.

Indexed as

AdultAgedAged, 80 and overBiomarkersBlood GlucoseChinaCoronary DiseaseFemaleGlucose Metabolism DisordersHumansIncidenceMaleMiddle AgedPrognosisProspective StudiesRisk AssessmentBiomarkersBlood Glucosecardiovascular disease risk factorsepidemiologyfasting plasma glucosegroup‐based trajectory modelproportional hazard regression

Identifiers

PMID29440033
PMCPMC5850191

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.