Evidence map›Paper›PMID 29440908›Full record

ArticleTherapeutics and clinical risk management2018

Positive correlation of the serum angiopoietin-like protein 3 levels with the aortic augmentation index in patients with coronary artery disease.

Yu-Shan Fu, Ji-Hung Wang, Chung-Jen Lee, Bang-Gee Hsu

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yu-Shan Fu *School of Medicine, Tzu Chi University, Hualien.
Ji-Hung Wang *School of Medicine, Tzu Chi University, Hualien.
Chung-Jen LeeDepartment of Nursing, Tzu Chi University of Science and Technology, Hualien.
Bang-Gee HsuSchool of Medicine, Tzu Chi University, Hualien.
Tzu Chi University · TWTzu Chi College of Technology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAngiopoietin-like protein 3 (ANGPTL3) plays an important role in lipid metabolism and angiogenesis and is elevated in familial hypercholesterolemia, metabolic syndrome, and insulin resistance. This study aims to evaluate the relationship between the fasting serum ANGPTL3 levels and the aortic augmentation index (AIx) in patients with coronary artery disease (CAD). MATERIALS AND

methodsFasting blood samples were obtained from 100 patients with CAD. The AIx was measured using a validated tonometry system (SphygmoCor). The serum ANGPTL3 levels were assessed using a commercial enzyme-linked immunosorbent assay kit.

resultsThe aortic AIx values were higher in female patients with CAD (

conclusionThe fasting serum ANGPTL3 level positively correlated with the aortic AIx values among patients with CAD.

Indexed as

ANGPTL3aortic augmentation indexarterial stiffnessheightischemic heart diseaseSphygmoCor

Identifiers

PMID29440908
PMCPMC5804136
OpenAlexW2791990734

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.