Evidence map›Paper›PMID 29468404›Full record

ArticleMolecular imaging and biology2018

Evaluation of Pancreatic VMAT2 Binding with Active and Inactive Enantiomers of [

Mika Naganawa, Keunpoong Lim, Nabeel B Nabulsi, Shu-Fei Lin, David Labaree, Jim Ropchan, Kevan C Herold, Yiyun Huang, Paul Harris, Masanori Ichise and 2 more

Abstract read
In one paragraph

Article in Molecular imaging and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Radiopharmaceuticals and their applications in medicine.Signal transduction and targeted therapy · 2025
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  4. Will extended field-of-view PET/CT depopulate the graveyard of failed PET radiopharmaceuticals?Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
    Review
  5. Article
  6. Review
  7. Review
  8. A Purification Method ofFrontiers in medicine · 2021
    Article
  9. Beta Cell Imaging-From Pre-Clinical Validation to First in Man Testing.International journal of molecular sciences · 2020
    Review
  10. Review
  11. Tobacco Smoking in People Is Not Associated with Altered 18-kDa Translocator Protein Levels: A PET Study.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
  12. Quantification of PET infusion studies without true equilibrium: A tissue clearance correction.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  13. PET Imaging of Pancreatic Dopamine DJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
  14. Article
  15. Review
  16. Molecular imaging of β-cells: diabetes and beyond.Advanced drug delivery reviews · 2019
    Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Mika NaganawaYale University, P.O. Box 208048, New Haven, CT, 06520-8048, USA. mika.naganawa@yale.edu.ORCID http://orcid.org/0000-0002-4408-2621
Keunpoong LimYale University, P.O. Box 208048, New Haven, CT, 06520-8048, USA.
Nabeel B NabulsiYale University, P.O. Box 208048, New Haven, CT, 06520-8048, USA.
Shu-Fei LinYale University, P.O. Box 208048, New Haven, CT, 06520-8048, USA.
David LabareeYale University, P.O. Box 208048, New Haven, CT, 06520-8048, USA.
Jim RopchanYale University, P.O. Box 208048, New Haven, CT, 06520-8048, USA.
Kevan C HeroldYale University, P.O. Box 208048, New Haven, CT, 06520-8048, USA.
Yiyun HuangYale University, P.O. Box 208048, New Haven, CT, 06520-8048, USA.
Paul HarrisColumbia University, New York, NY, USA.
Masanori IchiseColumbia University, New York, NY, USA.
Gary W ClineYale University, P.O. Box 208048, New Haven, CT, 06520-8048, USA.
Richard E CarsonYale University, P.O. Box 208048, New Haven, CT, 06520-8048, USA.
Yale University · USColumbia University · US

Funding

Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Imaging beta cell function for metabolic surgeryR01DK104740 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HARRIS, PAUL E · 2015 to 2019
$2.5M
PET imaging of human beta cell massR01DK077493 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HARRIS, PAUL E · 2006 to 2008
$1.7M
State-of-the-Art Small Animal PET/CT InstrumentationS10OD010322 · OD · YALE UNIVERSITY · PI CARSON, RICHARD E. · 2013 to 2013
$595k
NCATS NIH HHS UL1 TR000142NIDDK NIH HHS R01 DK077493NIDDK NIH HHS R01 DK104740NIH HHS S10 OD010322
6 · The paper itself

Abstract

purposePrevious studies demonstrated the utility of [ PROCEDURES: Six HCs and four T1DM patients were scanned on separate days after injection of [

results[

conclusionsNon-displaceable uptake was different among organs and between enantiomers. Use of scaled spleen V

Indexed as

AdultCase-Control StudiesDiabetes Mellitus, Type 1FemaleFluorine RadioisotopesHumansInjectionsMaleStereoisomerismTetrabenazineVesicular Monoamine Transport ProteinsYoung Adultflorbenazine F 18Fluorine RadioisotopesTetrabenazineVesicular Monoamine Transport Proteins[18F]FP-(+)-DTBZ[18F]FP-(−)-DTBZPancreas non-displaceable uptakePETVesicular monoamine transporter type 2

Identifiers

PMID29468404
PMCPMC6533199
OpenAlexW2790946334

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.