Evidence map›Paper›PMID 29477121›Full record

ReviewCurrent opinion in cell biology2018

Ultrastructure of the actin cytoskeleton.

Tatyana M Svitkina

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Proteomic Analysis of Dairy Cows with Persistent Subclinical Hypocalcemia.Animals : an open access journal from MDPI · 2026
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  5. Review
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  12. Review
  13. GALNT9 enrichment attenuates MPPBiology direct · 2024
    Article
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  15. Article
  16. Article
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  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Tatyana M SvitkinaDepartment of Biology, University of Pennsylvania, 433 S. University Avenue, Philadelphia, PA 19104, USA. Electronic address: svitkina@sas.upenn.edu.

Funding

Multifaceted roles of nonmuscle myosin II in cell adhesion and migrationR01GM095977 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI SVITKINA, TATYANA · 2013 to 2020
$2.7M
NIGMS NIH HHS R01 GM095977
6 · The paper itself

Abstract

The actin cytoskeleton is the primary force-generating machinery in the cell, which can produce pushing (protrusive) forces using energy of actin polymerization and pulling (contractile) forces via sliding of bipolar filaments of myosin II along actin filaments, as well as perform other key functions. These functions are essential for whole cell migration, cell interaction with the environment, mechanical properties of the cell surface and other key aspects of cell physiology. The actin cytoskeleton is a highly complex and dynamic system of actin filaments organized into various superstructures by multiple accessory proteins. High resolution architecture of functionally distinct actin arrays provides key clues for understanding actin cytoskeleton functions. This review summarizes recent advance in our understanding of the actin cytoskeleton ultrastructure.

Indexed as

Actin CytoskeletonActinsAnimalsCell Surface ExtensionsCytokinesisHumansModels, BiologicalStress FibersActins

Identifiers

PMID29477121
PMCPMC6103910

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.