Evidence map›Paper›PMID 29487613›Full record

ArticleFrontiers in genetics2018

Digital Twins in Health Care: Ethical Implications of an Emerging Engineering Paradigm.

Koen Bruynseels, Filippo Santoni de Sio, Jeroen van den Hoven

Abstract read
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 162 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

162 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Digital Twins and Health Care: an Umbrella Review.Journal of medical systems · 2025
    Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Future-Making From Afar: Digital Twins in Medicine.Sociology of health & illness · 2026
    Article
  15. Article
  16. [Digital twins in uro-oncology].Urologie (Heidelberg, Germany) · 2026
    Review
  17. Review
  18. Review
  19. Review
  20. Article

102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Koen BruynseelsDepartment of Philosophy, Faculty of Technology, Policy and Management, Delft University of Technology, Delft, Netherlands.
Filippo Santoni de SioDepartment of Philosophy, Faculty of Technology, Policy and Management, Delft University of Technology, Delft, Netherlands.
Jeroen van den HovenDepartment of Philosophy, Faculty of Technology, Policy and Management, Delft University of Technology, Delft, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Personalized medicine uses fine grained information on individual persons, to pinpoint deviations from the normal. 'Digital Twins' in engineering provide a conceptual framework to analyze these emerging data-driven health care practices, as well as their conceptual and ethical implications for therapy, preventative care and human enhancement. Digital Twins stand for a specific engineering paradigm, where individual physical artifacts are paired with digital models that dynamically reflects the status of those artifacts. When applied to persons, Digital Twins are an emerging technology that builds on

Indexed as

digital twinsethics of biomedical dataethics of human enhancementpersonalized medicineprivacy in healthcare technologiestherapyvalue sensitive design in healthcare technologiesvirtual self

Identifiers

PMID29487613
PMCPMC5816748

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.