← Insulin × glycemic control

SynthesisMedicine2018

Effect of hypoglycemic agents on survival outcomes of lung cancer patients with diabetes mellitus: A meta-analysis.

Wen-Xiu Xin et al.PubMed ↗Full text ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation · may be no link

No clear link with glycemic control

−5%−21% to +13%

Smaller than almost all for glycemic control

As reported

HR 0.95, 95% CI 0.79–1.13

Correlation · may be no link

No clear link with glycemic control

+3%−24% to +41%

Smaller than almost all for glycemic control

As reported

HR 1.03, 95% CI 0.76–1.41

Correlation · may be no link

No clear link with deaths

+10%−13% to +40%

Bigger than 3 in 10 for all-cause mortality

As reported

HR 1.10, 95% CI 0.87–1.40 · the paper's word: All-cause mortality

+1 more in the walkthrough ↓

Four numbers in the abstract

the abstract, start to end

… between insulin and OS (n = 2, HR: 0.95, 95% CI: 0.79-1.13) or CSS (n = 2, HR: 1.03, 95% CI: 0.76-1.41) was noted.

… and reported no clinical benefit (HR: 1.10, 95% CI: 0.87-1.40).

… with lung cancer survival (HR: 1.04, 95% CI: 0.65-1.66).

← favours treatmentfavours comparator →
could be chance
Glycemic control
HR 0.950.79–1.13
Glycemic control
HR 1.030.76–1.41
All-cause mortality
HR 1.100.87–1.40
All-cause mortality
HR 1.040.65–1.66
Sulfonylureas & glinidesThiazolidinedionesInsulinGlycemic controlAll-cause mortality
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Full record →Abstract, authors, funding and every citing paper · PMID 29489653