Evidence mapPaperPMID 29496507Full record

ArticleDiabetes research and clinical practice2018

IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045.

N H Cho, J E Shaw, S Karuranga, Y Huang, J D da Rocha Fernandes, A W Ohlrogge, B Malanda

20 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Diabetes research and clinical practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT04183868. Cited by 2,973 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2,973citing papers in PubMed, 9 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04183868 phase4completed

Comparative Effects of Empagliflozin Versus Glimepiride After 26-weeks of Treatment Add on Metformin on Myocardial Metabolic Rate of Glucose Estimated Through 18FDG-PET in Patients With Type 2 Diabetes

Ran2016Enrolled26Registered outcomes10Posted comparisons0ConditionsCardiovascular Risk Factor, Type 2 DiabetesArmsempagliflozin 10 mg, Glimepiride 2 mg
Open the trial in the graph
NCT04215445 phase4unknown statusstarted 2019, after this paper: background citation

Effect of Sodium Glucose co Transporter 2 (SGLT2) Inhibition on Optical Coherence Tomography Angiography (OCT-A) Parameters in Diabetic Chronic Kidney Disease (CKD)

Ran2019Enrolled90Registered outcomes3Posted comparisons0ConditionsChronic Kidney Diseases, Diabetes Mellitus, Diabetic RetinopathyArmsempagliflozin 25 mg, OCT-A
Open the trial in the graph
NCT05613400 phase4unknown statusstarted 2022, after this paper: background citation

The Effect of Simvastatin on Bone Density in Postmenopausal Women With Type 2 Diabetes: a Double-blind, Randomized Active-comparator (Ezetimibe) Controlled Clinical Trial

Ran2022Enrolled240Registered outcomes7Posted comparisons0ConditionsDiabetes Mellitus, Type 2ArmsEzetimibe 10mg, Simvastatin 10mg
Open the trial in the graph
NCT06064669 narecruitingstarted 2024, after this paper: background citation

Effect of Metformin on Healthy Live Birth After In-vitro Fertilization in Women With Prediabetes Mellitus: a Multicenter Double-blind Placebo Controlled Randomized Trial

Ran2024Enrolled988Registered outcomes26Posted comparisons0ConditionsIn-Vitro Fertilization, Metformin, PrediabetesArmsMetformin pretreatment before endometrial preparation for frozen embryo transfer, Metformin pretreatment before ovarian stimulation, Placebo pretreatment before endometrial preparation for frozen embryo transfer, Placebo pretreatment before ovarian stimulation
Open the trial in the graph
NCT03835312 narecruitingnot on this mapstarted 2019, after this paper: background citation

Sequential Transplantation of Umbilical Cord Blood Stem Cells and Islet Cells in Children and Adolescents With Monogenic Immunodeficiency Type 1 Diabetes Mellitus

TypeinterventionalSponsorChildren's Hospital of Fudan UniversityRan2019 to 2030Enrolled50ConditionsDiabetes Mellitus, Type 1, Immunologic Deficiency SyndromesArmsSequential transplantation
NCT03914924 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Effects of an Exercise and Lifestyle Education Program for People With Diabetes and Prediabetes: A Multicenter Randomized Controlled Trial

TypeinterventionalSponsorFederal University of Juiz de ForaRan2020 to 2025Enrolled240ConditionsDiabetes Mellitus, PrediabetesArmsExercise Program, Lifestyle Education Program
NCT03997396 unknown statusnot on this mapstarted 2019, after this paper: background citation

Effects of Gestational Giabetes Mellitus on Neuropsychological Development and Physique Growth in Children:a Cohort Study

TypeobservationalSponsorChen LiRan2019 to 2025Enrolled510ConditionsGestational Diabetes Mellitus, Children
NCT04105348 unknown statusnot on this mapstarted 2019, after this paper: background citation

The Association of Diabetes Mellitus and Inflammatory Bowel Disease

TypeobservationalSponsorAssiut UniversityRan2019 to 2021Enrolled100ConditionsInflammatory Bowel DiseasesArmsHbA1c
NCT04267367 nacompletednot on this mapstarted 2021, after this paper: background citation

Effectiveness of Dietitian-led Dietary Approach to Management of Diabetes (DIAM-D) in Tertiary Care Hospital of Nepal: a Randomized Control Trial

TypeinterventionalSponsorPurbanchal UniversityRan2021 to 2022Enrolled156ConditionsDiabetesArmsDietitian-led dietary approach to management of diabetes
NCT04477694 unknown statusnot on this mapstarted 2020, after this paper: background citation

The Effect of Diabetes Mellitus on Hemodynamics, Procedure Times, Anesthetic Consumption and Complications in Colonoscopy Under Sedoanalgesia

TypeobservationalSponsorBaskent UniversityRan2020 to 2023Enrolled100ConditionsDiabetes Mellitus, Type 2, SedoanalgesiaArmscolonoscopy under sedoanalgesia
NCT04841291 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Feasibility of Virtual Simulation-Based Diabetes Foot Care Education in Patients With Diabetes in Ethiopia

TypeinterventionalSponsorFisseha Z AmdieRan2022 to 2024Enrolled40ConditionsDiabetes Foot CareArmsDiabetes Foot Care Education (DFCE)
NCT04946188 nacompletednot on this mapstarted 2020, after this paper: background citation

Non-invasive Monitoring to Translate the Biometric Data of Participants With Diabetes Into Blood Glucose Levels

TypeinterventionalSponsorScimita Operations Pty Ltd.Ran2020 to 2020Enrolled14ConditionsDiabetes Type 2ArmsOpuz NICGM
NCT05349357 nacompletednot on this mapstarted 2022, after this paper: background citation

Compare the Effects of Sliding With Tensioner Technique of Neural Mobilization in Diabetic Peripheral Neuropathy Patients

TypeinterventionalSponsorRiphah International UniversityRan2022 to 2023Enrolled32ConditionsDiabetic Peripheral Neuropathic PainArmsSliding Neural mobilization, Tensioner Neural mobilization, Stretching exercises, TENS
NCT05422235 nacompletednot on this mapstarted 2022, after this paper: background citation

Comparison of the Effects of Different Exercise Programs on Lower Extremity Distal Tissue Mechanics, Muscle Strength and Neuropathy Symptoms in Type 2 Diabetics With Peripheral Neuropathy

TypeinterventionalSponsorEastern Mediterranean UniversityRan2022 to 2025Enrolled74ConditionsDiabetic Foot, Peripheral Neuropathy With Type 2 DiabetesArmsRoutine Medical Treatment, Aerobic Exercise, Aerobic Exercise+ Foot-Related Exercise
NCT05609266 completednot on this map

Validation of Non-invasive Risk Models for Prediction of Incident Type 2 Diabetes in a Swedish Population

TypeobservationalSponsorUmeå UniversityRan1990 to 2020Enrolled115,642ConditionsType2diabetes
NCT06299800 unknown statusnot on this mapstarted 2024, after this paper: background citation

Type 2 Diabetes Mellitus and Cancer: Phenotyping of Patients at a Third-level Diabetes Centre

TypeobservationalSponsorAzienda Ospedaliero Universitaria Maggiore della CaritaRan2024 to 2025Enrolled779ConditionsDiabetes Mellitus, Type 2, CancerArmsphenotyping of patients followed at a third-level diabetes centre with cancer
NCT06469437 narecruitingnot on this mapstarted 2024, after this paper: background citation

The Impact of Geriatric Assessment on the Treatment Plan of Elderly Patients With Type 2 Diabetes Mellitus: a Randomized Clinical Trial.

TypeinterventionalSponsorHospital de Clinicas de Porto AlegreRan2024 to 2028Enrolled220ConditionsType2diabetes, Frail Elderly Syndrome, Frailty, Geriatric AssessmentArmsProviding the physicians with a proposed glycated hemoglobin target
NCT06478173 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effect of Complex Exercise Training on General Health Status in Patients with Type 2 Diabetes

TypeinterventionalSponsorUniversity of the Faroe IslandsRan2024 to 2024Enrolled126ConditionsType2diabetesArmsExercise training
NCT06518486 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effectiveness of Foot-Ankle Exercise and Walking Exercise on Foot Neuropathy, Stress, Quality of Life, Blood Sugar Markers, Blood Pressure, Ankle-Brachial Index, and BMI Among Diabetes Mellitus Patients

TypeinterventionalSponsorTaipei Medical UniversityRan2024 to 2025Enrolled375ConditionsDiabetic Foot, Diabetes Mellitus, Type 2, Diabetic Neuropathies, Diabetes Type 2ArmsFoot-ankle exercise, Walking exercise, Usual care and health education
NCT07270328 nacompletednot on this mapstarted 2024, after this paper: background citation

A Pilot Study of Feasibility and Exploratory Study for a Definitive Randomised Controlled Trial of Foot-Ankle Versus Walking Exercises in Patients With Diabetes Mellitus: Effects on Neuropathy, Stress, and Quality of Life

TypeinterventionalSponsorTaipei Medical UniversityRan2024 to 2024Enrolled108ConditionsDiabete Mellitus, Diabete Type 2, Diabetic Peripheral Neuropathy, Diabetic FootArmsFoot-ankle exercise group, Walking exercise group, Control group
3 · Its place in the literature

Who cites it

2,973 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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2,913 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

N H ChoInternational Diabetes Federation, Chaussee de la Hulpe 166, Brussels, Belgium; Department of Preventive Medicine, Ajou University School of Medicine, 164 World Cup-ro, Suwon, South Korea. Electronic address: chnaha@ajou.ac.kr.
J E ShawBaker Heart and Diabetes Institute, 75 Commercial Rd, Melbourne, Australia. Electronic address: jonathan.shaw@bakeridi.edu.au.
S KarurangaInternational Diabetes Federation, Chaussee de la Hulpe 166, Brussels, Belgium. Electronic address: suvi.karuranga@idf.org.
Y HuangInternational Diabetes Federation, Chaussee de la Hulpe 166, Brussels, Belgium. Electronic address: yadi.huang@idf.org.
J D da Rocha FernandesInternational Diabetes Federation, Chaussee de la Hulpe 166, Brussels, Belgium. Electronic address: jdfe@novonordisk.com.
A W OhlroggeInternational Diabetes Federation, Chaussee de la Hulpe 166, Brussels, Belgium. Electronic address: anne.ohlrogge@idf.org.
B MalandaInternational Diabetes Federation, Chaussee de la Hulpe 166, Brussels, Belgium. Electronic address: belma.malanda@idf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSince the year 2000, IDF has been measuring the prevalence of diabetes nationally, regionally and globally.

aimTo produce estimates of the global burden of diabetes and its impact for 2017 and projections for 2045.

methodsA systematic literature review was conducted to identify published studies on the prevalence of diabetes, impaired glucose tolerance and hyperglycaemia in pregnancy in the period from 1990 to 2016. The highest quality studies on diabetes prevalence were selected for each country. A logistic regression model was used to generate age-specific prevalence estimates or each country. Estimates for countries without data were extrapolated from similar countries.

resultsIt was estimated that in 2017 there are 451 million (age 18-99 years) people with diabetes worldwide. These figures were expected to increase to 693 million) by 2045. It was estimated that almost half of all people (49.7%) living with diabetes are undiagnosed. Moreover, there was an estimated 374 million people with impaired glucose tolerance (IGT) and it was projected that almost 21.3 million live births to women were affected by some form of hyperglycaemia in pregnancy. In 2017, approximately 5 million deaths worldwide were attributable to diabetes in the 20-99 years age range. The global healthcare expenditure on people with diabetes was estimated to be USD 850 billion in 2017.

conclusionThe new estimates of diabetes prevalence, deaths attributable to diabetes and healthcare expenditure due to diabetes present a large social, financial and health system burden across the world.

Indexed as

AdolescentAdultAgedAged, 80 and overDiabetes MellitusFemaleForecastingGeographyGlobal HealthGlucose IntoleranceHealth ExpendituresHumansHyperglycemiaMaleMiddle AgedPregnancyDiabetes prevalenceEpidemiologyGestational diabetesHealth economicsImpaired glucose toleranceMortality

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

and 14 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.