Evidence map›Paper›PMID 29500244›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Anticancer Mechanisms in Two Murine Bone Marrow-Derived Dendritic Cell Subsets Activated with TLR4 Agonists.

Alexander Bagaev, Aleksey Pichugin, Edward L Nelson, Michael G Agadjanyan, Anahit Ghochikyan, Ravshan I Ataullakhanov

Abstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Dendritic cell immunotherapy has its antitumor action improved by the LPS in the maturation process.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander BagaevThe Institute of Immunology, Federal Medical-Biological Agency, Moscow 115478, Russia.ORCID 0000-0002-8680-854X
Aleksey PichuginThe Institute of Immunology, Federal Medical-Biological Agency, Moscow 115478, Russia.ORCID 0000-0001-5356-3331
Edward L NelsonDepartment of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA 92697.ORCID 0000-0001-7887-032X
Michael G AgadjanyanDepartment of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA 92647; and.
Anahit GhochikyanDepartment of Molecular Immunology, Institute for Molecular Medicine, Huntington Beach, CA 92647; and aghochikyan@immed.org ravshan.ataullakhanov@gmail.com.ORCID 0000-0001-5436-0616
Ravshan I AtaullakhanovThe Institute of Immunology, Federal Medical-Biological Agency, Moscow 115478, Russia; aghochikyan@immed.org ravshan.ataullakhanov@gmail.com.ORCID 0000-0002-4767-6409

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
NCI NIH HHS P30 CA062203
6 · The paper itself

Abstract

Dendritic cells (DCs) are well-known for their functions in orchestrating the innate and adaptive arms of immune defense. However, under certain conditions, DCs can exert tumoricidal activity. We have elucidated the mechanism of tumor suppression by TLR4-activated bone marrow-derived DCs (BMDCs) isolated from BALB/c mice. We identified that two distinct subsets of BMDCs (CD11b

Indexed as

AnimalsBone MarrowBone Marrow CellsCD11c AntigenCell Line, TumorCells, CulturedDendritic CellsFemaleInterferon-betaMiceMice, Inbred BALB CMice, Inbred C57BLToll-Like Receptor 4Tumor MicroenvironmentCD11c AntigenInterferon-betaTlr4 protein, mouseToll-Like Receptor 4

Identifiers

PMID29500244
PMCPMC5962282

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.