Evidence mapPaperPMID 29527621Full record

Observational studyActa diabetologica2018

Predictors of treatment response to liraglutide in type 2 diabetes in a real-world setting.

N Simioni, C Berra, M Boemi, A C Bossi, R Candido, G Di Cianni, S Frontoni, S Genovese, P Ponzani, V Provenzano and 6 more

Full text readMulticenter StudyObservational Study
In one paragraph

Observational study in Acta diabetologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
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  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

N SimioniPresidio Ospedaliero di Cittadella, Cittadella, Padua, Italy.
C BerraHumanitas Research Hospital, Rozzano, MI, Italy.
M BoemiIRCCS INRCA, Ancona, Italy.
A C BossiASST Bergamo Ovest, Treviglio, BG, Italy.
R CandidoAzienda Sanitaria Universitaria Integrata di Trieste, Trieste, Italy.
G Di CianniOspedale di Livorno, Livorno, Italy.
S FrontoniUniversity of Rome Tor Vergata, Rome, Italy.
S GenoveseIRCCS Centro Cardiologico Monzino, Milan, Italy.
P PonzaniOspedale La Colletta, ASL3 Genovese, Arenzano, Italy.
V ProvenzanoCentro Regionale di Riferimento Diabetologia ed Impianto Microinfusori Sicilia, Partinico, Palermo, Italy.
G T RussoUniversity of Messina, Messina, Italy.
L SciangulaIRCCS Multimedica - Ospedale di Castellanza, Varese, Italy.
A LapollaUniversity of Padua, Padua, Italy.
C BetteNovo Nordisk Spa, Rome, Italy.
M C RossiCORESEARCH - Center for Outcomes Research and Clinical Epidemiology, Via Tiziano Vecellio, 2, 65124, Pescara, Italy. rossi@coresearch.it.ORCID http://orcid.org/0000-0001-8696-4238
ReaL (NN2211-4118) Study Group*

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThere is an unmet need among healthcare providers to identify subgroups of patients with type 2 diabetes who are most likely to respond to treatment.

methodsData were taken from electronic medical records of participants of an observational, retrospective study in Italy. We used logistic regression models to assess the odds of achieving glycated haemoglobin (HbA

resultsData from 1325 patients were included, of which 577 (43.5%) achieved HbA

conclusionsGlycaemic response to liraglutide is largely driven by baseline HbA

Indexed as

AgedBiomarkersBlood GlucoseDatabases, FactualDiabetes Mellitus, Type 2Electronic Health RecordsFemaleGlycated HemoglobinHumansHypoglycemic AgentsItalyLiraglutideLongitudinal StudiesMaleMiddle AgedPrognosisBiomarkersBlood GlucoseGlycated HemoglobinHypoglycemic AgentsLiraglutideGLP-1RALiraglutideRECPAM analysisResponse to therapyType 2 diabetes

Identifiers

PMID29527621
PMCPMC5959971

What Socratic holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.