Evidence map›Paper›PMID 29532291›Full record

Trial reportIrish journal of medical science2019

The effect of CYP1A2 genotype on the ergogenic properties of caffeine during resistance exercise: a randomized, double-blind, placebo-controlled, crossover study.

Rahman Rahimi

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Irish journal of medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Effect ofNutrients · 2024
    Trial
  10. Influence of the CYP1A2 c.European journal of nutrition · 2024
    Trial
  11. Trial
  12. Effect ofNutrients · 2024
    Trial
  13. Trial
  14. TheNutrients · 2023
    Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rahman RahimiDepartment of Exercise Physiology, University of Kurdistan, Sanandaj, Kurdistan, 416, Islamic Republic of Iran. rahman.rahimi@yahoo.com.ORCID http://orcid.org/0000-0002-4302-1472
University of Kurdistan · IR

Funding

University of Kurdistan grant number 14/20137; Monday, 13 July 2015
6 · The paper itself

Abstract

aimThe purpose of this study was to examine the effect of CYP1A2 -163C>A polymorphism on the ergogenic effects of caffeine supplementation during a resistance exercise (RE) session.

methodsIn a randomized, double-blind, placebo (PL)-controlled, crossover study, 30 resistance-trained men took part in two RE sessions (three sets to failure at 85% of one repetition maximum, 2-min rest between sets), including bench press (BP), leg press (LP), seated cable row, and shoulder press (SP) following caffeine (CAF) (6 mg kg

resultsThe two-way ANOVA with repeated measures revealed differences between AAs and AC/CCs under CAF conditions for repetitions performed in sets 1, 2, and 3 of BP (F

conclusionIn conclusion, acute ingestion of CAF significantly enhanced RE performance in resistance-trained men who were homozygous for the A allele, but not for C allele carriers. Further studies are needed to replicate the potential role of the CYP1A2 -163C>A polymorphism on the ergogenic effects of CAF in other modes of exercise and in other populations.

Indexed as

Polymorphism, Single NucleotideResistance TrainingAdultAllelesCaffeineCentral Nervous System StimulantsCross-Over StudiesCytochrome P-450 CYP1A2Double-Blind MethodExerciseGenotypeHeterozygoteHomozygoteHumansMalePerformance-Enhancing SubstancesCaffeineCentral Nervous System StimulantsCYP1A2 protein, humanCytochrome P-450 CYP1A2Performance-Enhancing SubstancesCaffeineCYP1A2 -163C>A polymorphismResistance exercise

Identifiers

PMID29532291
OpenAlexW2792953184

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.