Evidence map›Paper›PMID 29540479›Full record

ArticleThe Journal of biological chemistry2018

PcxL and HpxL are flavin-dependent, oxime-forming

Michelle N Goettge, Joel P Cioni, Kou-San Ju, Katharina Pallitsch, William W Metcalf

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. A Novel Biosynthetic Gene Cluster Across theMolecular plant-microbe interactions : MPMI · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Michelle N GoettgeFrom the Department of Microbiology and the Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, Illinois 61801 and.
Joel P CioniFrom the Department of Microbiology and the Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, Illinois 61801 and.
Kou-San JuFrom the Department of Microbiology and the Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, Illinois 61801 and.
Katharina Pallitschthe Institute of Organic Chemistry, University of Vienna, 1090 Vienna, Austria.
William W MetcalfFrom the Department of Microbiology and the Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, Illinois 61801 and metcalf@illinois.edu.
University of Illinois Urbana-Champaign · USUniversity of Vienna · AT

Funding

Structural Elucidation and Biosynthesis P01GM077596 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI METCALF, WILLIAM W · 2007 to 2016
$15.3M
Request for a Varian 600 MHz NMR InstrumentS10RR028833 · NCRR · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI VAN DER DONK, WILFRED A. · 2011 to 2011
$600k
Austrian Science Fund FWF P 27987NCRR NIH HHS S10 RR028833NIGMS NIH HHS P01 GM077596
6 · The paper itself

Abstract

Several oxime-containing small molecules have useful properties, including antimicrobial, insecticidal, anticancer, and immunosuppressive activities. Phosphonocystoximate and its hydroxylated congener, hydroxyphosphonocystoximate, are recently discovered oxime-containing natural products produced by

Indexed as

AminesBacterial ProteinsCatalysisDinitrocresolsFlavin-Adenine DinucleotideKineticsNADPOxidation-ReductionOxidoreductasesOximesPhosphinic AcidsStreptomycesSubstrate Specificity4,6-dinitro-o-cresolAminesBacterial ProteinsDinitrocresolsFlavin-Adenine DinucleotideNADPOxidoreductasesOximesPhosphinic Acidsenzyme kineticsflavin adenine dinucleotide (FAD)natural product biosynthesisnicotinamideoxidaseoximephosphonatesphosphonic acidsubstrate specificity

Identifiers

PMID29540479
PMCPMC5936822
OpenAlexW2790327338

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.