Evidence map›Paper›PMID 29544467›Full record

ArticleBMC pregnancy and childbirth2018

Delayed Lactogenesis II and potential utility of antenatal milk expression in women developing late-onset preeclampsia: a case series.

Jill Demirci, Mandy Schmella, Melissa Glasser, Lisa Bodnar, Katherine P Himes

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05516199 (Antenatal Breastmilk Expression From Week 34 of Gestation Safety in Pregnancy and Benefits for the Newborn Infant), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05516199 nacompletednot on this mapstarted 2022, after this paper: background citation

Antenatal Breastmilk Expression From Week 34 of Gestation Safety in Pregnancy and Benefits for the Newborn Infant: A Pilot Randomized Study

TypeinterventionalSponsorOdense University HospitalRan2022 to 2023Enrolled60ConditionsBreastmilk Expression, Collection, Breastmilk, Breastfeeding, HealthyArmsAntenatal breastmilk expression, Breastfeeding consultation
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
  2. A National Survey: Trends in U.S. Postpartum Pumping Practices After Term Deliveries.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2025
    Article
  3. Article
  4. Factors Influencing Delayed Onset of Lactogenesis: A Scoping Review.International journal of general medicine · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jill DemirciDepartment of Health Promotion & Development, University of Pittsburgh School of Nursing, 440 Victoria Building, Pittsburgh, PA, 15261, USA. jvr5@pitt.edu.ORCID 0000-0002-4802-7849
Mandy SchmellaDepartment of Health Promotion & Development, University of Pittsburgh School of Nursing, 440 Victoria Building, Pittsburgh, PA, 15261, USA.
Melissa GlasserDepartment of Health Promotion & Development, University of Pittsburgh School of Nursing, 440 Victoria Building, Pittsburgh, PA, 15261, USA.
Lisa BodnarDepartment of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.
Katherine P HimesDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
University of Pittsburgh · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
NCATS NIH HHS UL1 TR001857NIH HHS UL1TR001857
6 · The paper itself

Abstract

backgroundPreeclampsia is a multi-system, hypertensive disorder of pregnancy that increases a woman's risk of later-life cardiovascular disease. Breastfeeding may counteract the negative cardiovascular sequela associated with preeclampsia; however, women who develop preeclampsia may be at-risk for suboptimal breastfeeding rates. In this case series, we present three cases of late-onset preeclampsia and one case of severe gestational hypertension that illustrate a potential association between hypertensive disorders of pregnancy and suboptimal breastfeeding outcomes, including delayed onset of lactogenesis II and in-hospital formula supplementation. CASE PRESENTATION: All cases were drawn from an ongoing pilot randomized controlled trial investigating the impact of antenatal milk expression versus an education control on breastfeeding outcomes. All study participants were healthy nulliparous women recruited at 34-36

conclusionsAdditional research is needed to address incidence, etiology, and interventions, including AME, for breastfeeding issues among a larger sample of women who develop hypertensive disorders of pregnancy.

Indexed as

AdultBreast FeedingBreast Milk ExpressionFemaleHumansHypertension, Pregnancy-InducedLactationLactation DisordersPre-EclampsiaPregnancyPrenatal CareTime FactorsYoung AdultBreast feedingBreast milk expressionHypertension, Pregnancy-inducedLactationPre-eclampsia

Identifiers

PMID29544467
PMCPMC5855986
OpenAlexW2793347854

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.