Evidence map›Paper›PMID 29545809›Full record

ReviewFrontiers in immunology2018

The Autoimmune Skin Disease Bullous Pemphigoid: The Role of Mast Cells in Autoantibody-Induced Tissue Injury.

Hui Fang, Yang Zhang, Ning Li, Gang Wang, Zhi Liu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Bullous pemphigoid.Nature reviews. Disease primers · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Proteases in Pemphigoid Diseases.Frontiers in immunology · 2019
    Review
  18. Review
  19. Observational
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Hui FangDepartment of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Yang ZhangDepartment of Dermatology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Ning LiDepartment of Dermatology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Gang WangDepartment of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Zhi LiuDepartment of Dermatology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
University of North Carolina at Chapel Hill · USAir Force Medical University · CNXijing Hospital · CN

Funding

IMMUNOPATHOGENESIS OF BULLOUS PEMPHIGOIDR01AI040768 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, ZHI · 2001 to 2016
$4.1M
Eosinophils in Bullous PemphigoidR01AR070276 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, ZHI · 2017 to 2021
$1.9M
NIAID NIH HHS R01 AI040768NIAMS NIH HHS R01 AR070276
6 · The paper itself

Abstract

Bullous pemphigoid (BP) is an autoimmune and inflammatory skin disease associated with subepidermal blistering and autoantibodies directed against the hemidesmosomal components BP180 and BP230. Animal models of BP were developed by passively transferring anti-BP180 IgG into mice, which recapitulates the key features of human BP. By using these

Indexed as

AnimalsAntibody-Dependent Cell CytotoxicityAutoantibodiesAutoantigensAutoimmune DiseasesCollagen Type XVIIDisease Models, AnimalHumansMast CellsNon-Fibrillar CollagensPemphigoid, BullousSkinAutoantibodiesAutoantigensCollagen Type XVIINon-Fibrillar Collagensautoantibodiesbullous pemphigoidhemidesmosomemast cellsskin autoimmunity

Identifiers

PMID29545809
PMCPMC5837973
OpenAlexW2791821174

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.