Evidence map›Paper›PMID 29565247›Full record

ArticleeLife2018

A gene-specific

Pei-Tseng Lee, Jonathan Zirin, Oguz Kanca, Wen-Wen Lin, Karen L Schulze, David Li-Kroeger, Rong Tao, Colby Devereaux, Yanhui Hu, Verena Chung and 12 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 198 papers.

0numbers the graph read from it
0cells of the map it votes in
198citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

198 citing papers in PubMed, 373 citations in OpenAlex.

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  11. Morphological innovation without gene co-option: thebioRxiv : the preprint server for biology · 2026
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  12. Drospondin, a glial glycoprotein with similarities to human Reelin/F-spondin, contributes toProceedings of the National Academy of Sciences of the United States of America · 2026
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138 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 1 country.

Pei-Tseng LeeDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID http://orcid.org/0000-0002-7501-7881
Jonathan ZirinDepartment of Genetics, Harvard Medical School, Boston, United States.
Oguz KancaDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Wen-Wen LinDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Karen L SchulzeDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID http://orcid.org/0000-0002-1368-729X
David Li-KroegerDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Rong TaoDepartment of Genetics, Harvard Medical School, Boston, United States.
Colby DevereauxDepartment of Genetics, Harvard Medical School, Boston, United States.
Yanhui HuDepartment of Genetics, Harvard Medical School, Boston, United States.
Verena ChungDepartment of Genetics, Harvard Medical School, Boston, United States.
Ying FangDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Yuchun HeDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Hongling PanDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Ming GeDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Zhongyuan ZuoDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Benjamin E HousdenDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID http://orcid.org/0000-0001-9134-4279
Stephanie E MohrDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID http://orcid.org/0000-0001-9639-7708
Shinya YamamotoDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID http://orcid.org/0000-0003-2172-8036
Robert W LevisDepartment of Embryology, Howard Hughes Medical Institute, Carnegie Institution for Science, Baltimore, United States.
Allan C SpradlingDepartment of Embryology, Howard Hughes Medical Institute, Carnegie Institution for Science, Baltimore, United States.
Norbert PerrimonDepartment of Genetics, Harvard Medical School, Boston, United States.ORCID http://orcid.org/0000-0001-7542-472X
Hugo J BellenDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID http://orcid.org/0000-0001-5992-5989
Baylor College of Medicine · USHoward Hughes Medical Institute · USHarvard University · US

Funding

VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI Geoffrey I. Shapiro · 1985 to 2026
$330.6M
Transposon induced disruption of most Drosophila genesR01GM067858 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J · 2003 to 2020
$15.7M
New collections of dsRNAs and overexpression miRNA constructs to supplement RNAiR01GM067761 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI PERRIMON, NORBERT · 2003 to 2019
$15.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
Steps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, NEUL, JEFFREY L · 2014 to 2019
$7.8M
Zebrafish CoreU54NS093793 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J · 2015 to 2022
$7.5M
Expansion and characterization of the Drosophila Toolkit to study SARS-CoV-2R24OD022005 · OD · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J · 2016 to 2023
$7.4M
Alzheimer's Association NIRH-15-364099Howard Hughes Medical InstituteNCI NIH HHS P30 CA006516NICHD NIH HHS U54 HD083092NICHD NIH HHS U54HD083092NIGMS NIH HHS GM067761NIGMS NIH HHS GM084947NIGMS NIH HHS R01 GM067761NIGMS NIH HHS R01 GM067858NIGMS NIH HHS R01 GM084947NIH HHS 5 P30 CA06516NIH HHS R01GM067858NIH HHS R24 OD022005NIH HHS R24OD02205NIH HHS U54NS093793NINDS NIH HHS U54 NS093793
6 · The paper itself

Abstract

We generated a library of ~1000

Indexed as

Gene LibraryAnimalsAnimals, Genetically ModifiedDrosophila melanogasterDrosophila ProteinsGene Expression ProfilingLuminescent ProteinsMutagenesis, InsertionalOrgan SpecificityTranscription FactorsDrosophila ProteinsGAL4 protein, DrosophilaLuminescent ProteinsTranscription Factorscassette excisionchromosomescomplementationCRIMICD. melanogasterGAL4/UASgene expressionloss of functionMiMIC

Identifiers

PMID29565247
PMCPMC5898912
OpenAlexW2790947724

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.