Evidence map›Paper›PMID 29569306›Full record

ArticleAngewandte Chemie (International ed. in English)2018

Optogenetic Control of Voltage-Gated Calcium Channels.

Guolin Ma, Jindou Liu, Yuepeng Ke, Xin Liu, Minyong Li, Fen Wang, Gang Han, Yun Huang, Youjun Wang, Yubin Zhou

Open access · hybridAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Cardiac optogenetics: shining light on signaling pathways.Pflugers Archiv : European journal of physiology · 2023
    Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Optogenetic Modulation of Ion Channels by Photoreceptive Proteins.Advances in experimental medicine and biology · 2021
    Review
  15. Article
  16. Optogenetic approaches to control CaCurrent opinion in physiology · 2020
    Article
  17. Review
  18. Review
  19. Review
  20. Optogenetic Control of Voltage-Gated Calcium Channels.Angewandte Chemie (International ed. in English) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Guolin MaInstitute of Biosciences and Technology, College of Medicine, Texas A&M University, 2121 W Holcombe Blvd, Houston, TX, 77030, USA.
Jindou LiuBeijing Key Laboratory of Gene Resource and Molecular, Development, College of Life Sciences, Beijing Normal University, Beijing, 100875, China.
Yuepeng KeInstitute of Biosciences and Technology, College of Medicine, Texas A&M University, 2121 W Holcombe Blvd, Houston, TX, 77030, USA.
Xin LiuInstitute of Biosciences and Technology, College of Medicine, Texas A&M University, 2121 W Holcombe Blvd, Houston, TX, 77030, USA.
Minyong LiDepartment of Medicinal Chemistry, Key Laboratory of Chemical Biology, School of Pharmacy, Shandong University, Jinan, Shandong, 250012, China.
Fen WangInstitute of Biosciences and Technology, College of Medicine, Texas A&M University, 2121 W Holcombe Blvd, Houston, TX, 77030, USA.
Gang HanDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
Yun HuangInstitute of Biosciences and Technology, College of Medicine, Texas A&M University, 2121 W Holcombe Blvd, Houston, TX, 77030, USA.
Youjun WangBeijing Key Laboratory of Gene Resource and Molecular, Development, College of Life Sciences, Beijing Normal University, Beijing, 100875, China.
Yubin ZhouInstitute of Biosciences and Technology, College of Medicine, Texas A&M University, 2121 W Holcombe Blvd, Houston, TX, 77030, USA.ORCID 0000-0001-7962-0517
Texas A&M University System · USBeijing Normal University · CNShandong University · CNUniversity of Massachusetts Chan Medical School · US

Funding

MOLECULAR CONTROL OF CALCIUM INFLUX AT THE ER-PLASMA MEMBRANE JUNCTIONSR01GM112003 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ZHOU, YUBIN · 2014 to 2022
$2.7M
TET-mediated epigenetic regulation in cardiac development.R01HL134780 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HUANG, YUN · 2018 to 2022
$1.9M
Optogenetic toolkit for remote control of voltage-gated calcium channelsR21GM126532 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HAN, GANG, ZHOU, YUBIN · 2018 to 2019
$443k
NHLBI NIH HHS R01 HL134780NIGMS NIH HHS R01 GM112003NIGMS NIH HHS R21 GM126532
6 · The paper itself

Abstract

Voltage-gated Ca

Indexed as

Calcium SignalingAnimalsCalciumCalcium ChannelsCell LineHEK293 CellsHumansMiceMonomeric GTP-Binding ProteinsMyocytes, CardiacOptogeneticsProtein EngineeringCalciumCalcium ChannelsMonomeric GTP-Binding Proteinscalcium signalingion channelsoptogeneticsprotein engineeringsynthetic biology

Identifiers

PMID29569306
PMCPMC6032918
OpenAlexW2789387318

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.