ArticleJournal of clinical hypertension (Greenwich, Conn.)2018
The risk of hypertension and cardiovascular disease in women with uterine fibroids.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups.Nature communications · 2025Pooled it
- Genetic liability to multiple factors and uterine leiomyoma risk: a Mendelian randomization study.Frontiers in endocrinology · 2023Pooled it
- Prevalence and associated risk factors of uterine fibroids in the Kingdom of Eswatini.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026Article
- Association between uterine fibroids and hypertension among women of reproductive age in Eastern Sudan: a matched case-control study.Scientific reports · 2026Article
- Improved Cardiometabolic Health with Uterine-Preserving Fibroid Treatment Compared to Hysterectomy.Journal of clinical medicine · 2026Article
- Construction and validation of risk prediction model for uterine fibroids: a retrospective cohort study based on MIMIC database.Reproductive biology and endocrinology : RB&E · 2026Article
- The Invisible Burden: Examining the Impact of Exposure Misclassification in Epidemiologic Analyses of Uterine Fibroids.Paediatric and perinatal epidemiology · 2026Article
- Association Between Uterine Fibroids and Risk of Atherosclerotic Cardiovascular Disease.Journal of the American Heart Association · 2026Article
- Increased risk of atrial fibrillation in uterine fibroid patients: a nationwide population-based study.Scientific reports · 2025Article
- Diabetes and Uterine Fibroid Diagnosis in Midlife: Study of Women's Health Across the Nation (SWAN).The Journal of clinical endocrinology and metabolism · 2025Article
- The Particularities of Arterial Hypertension in Female Sex: From Pathophysiology to Therapeutic Management.Journal of clinical medicine · 2025Review
- Blood Pressure, Cardiometabolic Traits, and Cardiovascular Events in Women With Uterine Fibroids: A Genetic Correlation and Mendelian Randomization Study.Journal of the American Heart Association · 2025Article
- Causal relationship between uterine fibroids and cardiovascular disease: A two-sample Mendelian randomization study.Medicine · 2025Article
- Impact of Uterine Leiomyomas on Cardiovascular Disease Risk in Young Reproductive-Aged Women: A Nationwide Population-Based Cohort Study.Journal of clinical medicine · 2025Article
- Epidemiological features of uterine fibroid-associated imaging changes in Chinese women of reproductive age: a retrospective study.BMJ open · 2025Observational
- Association between urinary cotinine level and hypertensive disorders of pregnancy in women with uterine myoma: findings from the Japan Environment and Children's Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Uterine fibroids show evidence of shared genetic architecture with blood pressure traits.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2025Article
- Endometriosis and uterine fibroids and risk of premature mortality: prospective cohort study.BMJ (Clinical research ed.) · 2024Article
- Body Mass Index and Uterine Fibroid Development: A Prospective Study.The Journal of clinical endocrinology and metabolism · 2024Article
- Hypoxia in uterine fibroids: role in pathobiology and therapeutic opportunities.Oxygen (Basel, Switzerland) · 2024Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Women with fibroids have a notably high hypertension risk. However, adjusted data regarding other cardiovascular disease (CVD) risk factors are scarce. In this cross-sectional study, CVD risk factors, hemodynamic parameters, and asymptomatic organ damage were analyzed between women with uterine fibroids and controls in a multi-ethnic population. In total, 104 women with self-reported fibroids and 624 controls were included. Women with fibroids had significantly higher odds to have hypertension (OR 3.4; 95% CI 2.2-5.2), diabetes (1.7; 1.0-2.9), and hypercholesterolemia (1.8; 1.1-3.2). After adjustment for confounders, only the odds ratio for hypertension was significant (1.8; 1.1-3.1). Asymptomatic organ damage occurred significantly more often in women with fibroids (66.7%; 95% CI 55.8%-77.6% vs 42.9%; 38.0-47.8 in controls), especially in the younger age group (respectively 48.5%; 31.1%-65.9% vs 22.1%; 17.0-27.2). In this study, women with fibroids had a remarkably high hypertension risk compared to controls, with more asymptomatic organ damage, in particular young women.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.