Evidence mapPaperPMID 29570616Full record

SynthesisNutrients2018

Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.

Ban-Hock Khor, Sreelakshmi Sankara Narayanan, Sharmela Sahathevan, Abdul Halim Abdul Gafor, Zulfitri Azuan Mat Daud, Pramod Khosla, Alice Sabatino, Enrico Fiaccadori, Karuthan Chinna, Tilakavati Karupaiah

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Article
  8. Impact of Dietary Fiber on Inflammation in Humans.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ban-Hock KhorDietetics Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia. khorbanhock@gmail.com.
Sreelakshmi Sankara NarayananDietetics Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia. sreelakshmiprem07@gmail.com.
Sharmela SahathevanDietetics Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia. sham_0901@yahoo.com.
Abdul Halim Abdul GaforDepartment of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia. halimgafor@gmail.com.
Zulfitri Azuan Mat DaudDepartment of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor 43400, Malaysia. zulfitri@upm.edu.my.ORCID 0000-0002-4017-107X
Pramod KhoslaDepartment of Nutrition & Food Sciences, College of Liberal Arts & Sciences, Wayne State University, Detroit, MI 48202, USA. aa0987@wayne.edu.
Alice SabatinoAcute and Chronic Renal Failure Unit, Department of Clinical and Experimental Medicine, University of Parma, 43126 Parma, Italy. alice.sabatino86@gmail.com.ORCID 0000-0003-2098-7597
Enrico FiaccadoriAcute and Chronic Renal Failure Unit, Department of Clinical and Experimental Medicine, University of Parma, 43126 Parma, Italy. enrico.fiaccadori@unipr.it.
Karuthan ChinnaDepartment of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. karuthan@gmail.com.
Tilakavati KarupaiahDietetics Program, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia. tilly_karu@yahoo.co.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low-grade chronic inflammation is prevalent in patients undergoing haemodialysis (HD) treatment and is linked to the development of premature atherosclerosis and mortality. The non-pharmacological approach to treat inflammation in HD patients through nutritional intervention is well cited. We aimed to assess the efficacy of different nutritional interventions at improving inflammatory outcomes in HD patients, based on markers such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumour necrosis factor-α (TNF-α). We searched PubMed, Cochrane Library, and Embase for randomized controlled trials (RCT) published before June 2017. Inclusion criteria included RCTs on adult patients on maintenance HD treatment with duration of nutritional interventions for a minimum 4 weeks. Risk of bias was assessed using the Jadad score. In total, 46 RCTs experimenting different nutritional interventions were included in the review and categorized into polyphenols rich foods, omega-3 fatty acids, antioxidants, vitamin D, fibres, and probiotics. Meta-analyses indicated significant reduction in CRP levels by omega-3 fatty acids (Random model effect: -0.667 mg/L,

Indexed as

Dietary SupplementsAdultAgedAntioxidantsBiomarkersDietary FiberFatty Acids, Omega-6FemaleHumansInflammationInflammation MediatorsMaleMiddle AgedNutritional StatusProbioticsRenal DialysisAntioxidantsBiomarkersDietary FiberFatty Acids, Omega-6Inflammation MediatorsVitamin DVitamin Eantioxidantsfibreshaemodialysisinflammationmeta-analysisnutritionomega-3 fatty acidspolyphenolssystematic review

Identifiers

PMID29570616
PMCPMC5946182

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.