Evidence map›Paper›PMID 29579192›Full record

ArticleEuropean heart journal2018

New prospects for PCSK9 inhibition?

Ulf Landmesser, M John Chapman, Jane K Stock, Pierre Amarenco, Jill J F Belch, Jan Borén, Michel Farnier, Brian A Ference, Stephan Gielen, Ian Graham and 14 more

Abstract readComment
PubMed Publisher
In one paragraph

Article in European heart journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors.

Ulf LandmesserDepartment of Cardiology, Charité - Universitätsmedizin Berlin (CBF), and Institute of Health (BIH), Berlin, Germany.
M John ChapmanNational Institute for Health and Medical Research (INSERM), University of Pierre and Marie Curie, Pitié-Salpêtrière Hospital, Paris, France.
Jane K StockEuropean Atherosclerosis Society, Gothenburg, Sweden.
Pierre AmarencoDepartment of Neurology and Stroke Centre, Bichat Hospital, Paris-Diderot-Sorbonne University, Paris, France.
Jill J F BelchInstitute of Cardiovascular Research, Ninewells Hospital and Medical School, Dundee, UK.
Jan BorénDepartment of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, and Wallenberg Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden.
Michel FarnierLipid Clinic, Point Medical, and Department of Cardiology, CHU Dijon-Bourgogne, Dijon, France.
Brian A FerenceDivision of Cardiovascular Medicine, Division of Translational Research and Clinical Epidemiology, Wayne State University School of Medicine, Detroit, MI, USA.
Stephan GielenMartin-Luther-University Halle/Wittenberg, University Hospital, Department of Internal Medicine III, Halle/Saale, Germany.
Ian GrahamTrinity College Dublin, Ireland.
Diederick E GrobbeeJulius Global Health, the Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
G Kees HovinghAcademic Medical Center, Department of Vascular Medicine, University of Amsterdam, Amsterdam, The Netherlands.
Thomas F LüscherUniversity Heart Center, Department of Cardiology, University Hospital Zurich, and Center for Molecular Cardiology, University of Zurich, Zurich, Switzerland.
Massimo F PiepoliG Da Saliceto Hospital, Heart Failure Unit, Cardiac Department, Piacenza, Italy.
Kausik K RayImperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, Imperial College, London, UK.
Erik S StroesAcademic Medical Center, Department of Vascular Medicine, University of Amsterdam, Amsterdam, The Netherlands.
Olov WiklundSahlgrenska University Hospital, Gothenburg, Sweden.
Stephan WindeckerDepartment of Cardiology, Swiss Cardiovascular Center, University Hospital, Bern, Switzerland.
Jose Luis ZamoranoDepartment of Cardiology, University Hospital Ramón y Cajal, Madrid, Spain.
Fausto PintoCardiology Department, CCUL, CAML, Faculdade de Medicina, Universidade de Lisboa, Portugal.
Lale TokgözogluDepartment of Cardiology, Hacettepe University, Ankara, Turkey.
Jeroen J BaxDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Alberico L CatapanoUniversity of Milan and Multimedica IRCSS Milano, Italy.
European Society of Cardiology/European Atherosclerosis Society Task Force

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiovascular DiseasesHyperlipoproteinemia Type IIHumansProprotein Convertase 9Proprotein ConvertasesSubtilisinsPCSK9 protein, humanProprotein Convertase 9Proprotein ConvertasesSubtilisins

Identifiers

PMID29579192

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.