Evidence map›Paper›PMID 29588609›Full record

ReviewClinical and experimental gastroenterology2018

Postoperative pancreatic fistula: a review of traditional and emerging concepts.

Christopher B Nahm, Saxon J Connor, Jaswinder S Samra, Anubhav Mittal

4 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Clinical and experimental gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 85 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 8 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04798560 unknown statusnot on this map

Risk Factors for Pancreaticojejunostomy Leakage Following Whipple Operation

Typeobservational_patient_registrySponsorDimitrios VourosRan2018 to 2022Enrolled100ConditionsPancreatic Fistula, Whipple Operation, Pancreaticoduodenectomy, POPFArmsPancreaticoduodenectomy
NCT05668260 nacompletednot on this mapstarted 2023, after this paper: background citation

Internal Biodegradable Stent Versus Non-Stent in Patients at High-Risk of Developing Fistula After Pancreatoduodenectomy (BioSteP): a Randomized Controlled Study

TypeinterventionalSponsorOspedale San RaffaeleRan2023 to 2026Enrolled122ConditionsPancreatoduodenectomy, Clinically Relevant Postoperative Pancreatic Fistula, Internal Biodegradable Pancreatic StentArmsBiodegradable Stent
NCT06198400 narecruitingnot on this mapstarted 2024, after this paper: background citation

Indocyanine Green Fluorescence in Evaluation of Post-resection Pancreatic Remnant Perfusion After Pancreaticoduodenectomy

TypeinterventionalSponsorCharles University, Czech RepublicRan2024 to 2027Enrolled60ConditionsPancreatic FistulaArmsPerioperative assessment of the perfusion of post-resection pancreatic remnant using indocyanine green-VerDye
NCT07248527 active not recruitingnot on this mapstarted 2025, after this paper: background citation

PAN-ICIS: Prospective Observational Study Evaluating the Intensive Care Infection Score for Early Detection of Infectious Complications After Pancreatic Resections

TypeobservationalSponsorCharles University, Czech RepublicRan2025 to 2028Enrolled400ConditionsPancreatectomy, Pancreatic Surgery, Intensive Care (ICU), Inflamatory Markers
3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 8 syntheses or guidelines pooled it, 199 citations in OpenAlex.

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  17. Regulating Enzyme Activity via Microaggregates Mediated by Phase Separation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  18. EUS pancreatic rendezvous to rescue failed ERCP for postoperative pancreatic fistula after pancreaticoduodenectomy.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2025
    Review
  19. Article
  20. Transpapillary drainage of pancreatic fluid leakageWorld journal of gastrointestinal endoscopy · 2025
    Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Christopher B NahmUpper Gastrointestinal Surgical Unit, Royal North Shore Hospital, Sydney, Australia.
Saxon J ConnorDepartment of Surgery, Christchurch Hospital, Christchurch, New Zealand.
Jaswinder S SamraUpper Gastrointestinal Surgical Unit, Royal North Shore Hospital, Sydney, Australia.
Anubhav MittalUpper Gastrointestinal Surgical Unit, Royal North Shore Hospital, Sydney, Australia.
Royal North Shore Hospital · AUChristchurch Hospital · NZThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative pancreatic fistula (POPF) remains the major cause of morbidity after pancreatic resection, affecting up to 41% of cases. With the recent development of a consensus definition of POPF, there has been a large number of reports examining various risk factors, prediction models, and mitigation strategies for this costly complication. Despite these strategies, the rates of POPF have not significantly diminished. Here, we review the literature and evidence regarding both traditional and emerging concepts in POPF prediction, prevention, and management. In particular, we review the evidence for the association between postoperative pancreatitis and POPF, and present a novel proposed mechanism for the development of POPF.

Indexed as

distal pancreatectomypancreaticoduodenectomypostoperative pancreatic fistulapostoperative pancreatitis

Identifiers

PMID29588609
PMCPMC5858541
OpenAlexW2791094629

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.