Evidence map›Paper›PMID 29623199›Full record

ReviewF1000Research2018

The physiological functions of central nervous system pericytes and a potential role in pain.

Nicholas Beazley-Long, Alexandra M Durrant, Matthew N Swift, Lucy F Donaldson

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicholas Beazley-LongArthritis Research UK Pain Centre & School of Life Sciences, Medical School, University of Nottingham, Nottingham, UK.ORCID https://orcid.org/0000-0001-7342-2771
Alexandra M DurrantArthritis Research UK Pain Centre & School of Life Sciences, Medical School, University of Nottingham, Nottingham, UK.
Matthew N SwiftArthritis Research UK Pain Centre & School of Life Sciences, Medical School, University of Nottingham, Nottingham, UK.
Lucy F DonaldsonArthritis Research UK Pain Centre & School of Life Sciences, Medical School, University of Nottingham, Nottingham, UK.
University of Nottingham · GB

Funding

Versus Arthritis 20400Versus Arthritis 21338
6 · The paper itself

Abstract

Central nervous system (CNS) pericytes regulate critical functions of the neurovascular unit in health and disease. CNS pericytes are an attractive pharmacological target for their position within the neurovasculature and for their role in neuroinflammation. Whether the function of CNS pericytes also affects pain states and nociceptive mechanisms is currently not understood. Could it be that pericytes hold the key to pain associated with CNS blood vessel dysfunction? This article reviews recent findings on the important physiological functions of CNS pericytes and highlights how these neurovascular functions could be linked to pain states.

Indexed as

Central Nervous SystemPainPericytes

Identifiers

PMID29623199
PMCPMC5861511
OpenAlexW2793225191

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.