Evidence map›Paper›PMID 29626933›Full record

Trial reportNutrition journal2018

Effects of nutrition therapy on HbA1c and cardiovascular disease risk factors in overweight and obese patients with type 2 diabetes.

Adham Mottalib, Veronica Salsberg, Barakatun-Nisak Mohd-Yusof, Wael Mohamed, Padraig Carolan, David M Pober, Joanna Mitri, Osama Hamdy

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrition journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02520050 nacompletednot on this map

The Effect of Three Different Models of Medical Nutrition Therapy (MNT) on Diabetes Control in Overweight and Obese Patients With Type 2 Diabetes: A Randomized Comparative Study. (Nutrition Path Study)

TypeinterventionalSponsorJoslin Diabetes CenterRan2015 to 2018Enrolled108ConditionsType 2 Diabetes, ObesityArmsTraditional MNT, Structured MNT, Structured MNT plus Weekly Support
NCT07030543 nacompletednot on this mapstarted 2025, after this paper: background citation

Feasibility Of Individualized Dietary Plan (Idp) On Glycemic Control And Total Cholestrol In Diabetic Patients At Diabetes Hospital And Research Centre Peshawar

TypeinterventionalSponsorKhyber Medical University PeshawarRan2025 to 2025Enrolled122ConditionsType 2 Diabetes MellitusArmsIndividualized Dietary Plan (IDP) for Type 2 Diabetes, Usual care
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Adham MottalibJoslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA, 02215, USA. adham.mottalib@joslin.harvard.edu.ORCID 0000-0002-8573-6329
Veronica SalsbergJoslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA, 02215, USA.
Barakatun-Nisak Mohd-YusofJoslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA, 02215, USA.
Wael MohamedJoslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA, 02215, USA.
Padraig CarolanJoslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA, 02215, USA.
David M PoberJoslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA, 02215, USA.
Joanna MitriJoslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA, 02215, USA.
Osama HamdyJoslin Diabetes Center, Harvard Medical School, One Joslin Place, Boston, MA, 02215, USA.
Joslin Diabetes Center · US

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
NIDDK NIH HHS P30 DK036836
6 · The paper itself

Abstract

backgroundNutrition Therapy (NT) is essential in type 2 diabetes (T2D) management. Standards of care recommend that each patient engages with a nutritionist (RDN) to develop an individualized eating plan. However, it is unclear if it is the most efficient method of NT. This study evaluates the effects of three different methods of NT on HbA1c and cardiovascular disease risk factors in overweight and obese patients with T2D.

methodsWe randomized 108 overweight and obese patients with T2D (46 M/62F; age 60 ± 10 years; HbA1c 8.07 ± 1.05%; weight 101.4 ± 21.1 kg and BMI 35.2 ± 7.7 kg/m

resultsAfter 16 weeks, all three groups had a significant reduction of their energy intake compared to baseline. HbA1c did not change from baseline in group A, but decreased significantly in groups B (- 0.66%, 95% CI -1.03 to - 0.30) and C (- 0.61%, 95% CI -1.0 to - 0.23) (p value for difference among groups over time < 0.001). Groups B and C also had significant reductions in body weight, body fat percentage and waist circumference.

conclusionStructured NT alone improves glycemia in comparison to individualized eating plans in overweight and obese patients with T2D. It also reduces other important cardiovascular disease risk factors like body fat percentage and waist circumference.

trial registrationThe trial was retrospectively registered at clinicaltrials.gov( NCT02520050 ).

Indexed as

Nutrition TherapyAgedBehavior TherapyBody CompositionBody Mass IndexCardiovascular DiseasesCounselingDiabetes Mellitus, Type 2Diet, ReducingFemaleGlycated HemoglobinHumansLife StyleMaleMealsMiddle AgedGlycated HemoglobinClinical nutritionDiabetes managementLifestyle interventionNutrition therapyWeight management

Identifiers

PMID29626933
PMCPMC5889846
OpenAlexW2796834847

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.