Evidence map›Paper›PMID 29643068›Full record

ArticleRNA (New York, N.Y.)2018

Hydrogen peroxide is a neuronal alarmin that triggers specific RNAs, local translation of Annexin A2, and cytoskeletal remodeling in Schwann cells.

Samuele Negro, Marco Stazi, Marta Marchioretto, Toma Tebaldi, Umberto Rodella, Elisa Duregotti, Volker Gerke, Alessandro Quattrone, Cesare Montecucco, Michela Rigoni and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Article
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  8. Article
  9. Review
  10. Spatial and Transcriptomic Analysis of Perineural Invasion in Oral Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Article
  11. Article
  12. Review
  13. The Actin Cytoskeleton in Myelinating Cells.Neurochemical research · 2020
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Samuele NegroDepartment of Biomedical Sciences, University of Padua, 35131 Padua, Italy.
Marco StaziDepartment of Biomedical Sciences, University of Padua, 35131 Padua, Italy.
Marta MarchiorettoInstitute of Biophysics, CNR Unit at Trento, 38123 Povo, Italy.
Toma TebaldiCentre for Integrative Biology, University of Trento, 38123 Povo, Italy.ORCID 0000-0002-0625-1631
Umberto RodellaDepartment of Biomedical Sciences, University of Padua, 35131 Padua, Italy.
Elisa DuregottiDepartment of Biomedical Sciences, University of Padua, 35131 Padua, Italy.
Volker GerkeInstitute of Medical Biochemistry, University of Münster, 48149 Münster, Germany.
Alessandro QuattroneCentre for Integrative Biology, University of Trento, 38123 Povo, Italy.ORCID 0000-0003-3333-7630
Cesare MontecuccoDepartment of Biomedical Sciences, University of Padua, 35131 Padua, Italy.ORCID 0000-0001-7361-5688
Michela RigoniDepartment of Biomedical Sciences, University of Padua, 35131 Padua, Italy.ORCID 0000-0003-1763-2648
Gabriella VieroInstitute of Biophysics, CNR Unit at Trento, 38123 Povo, Italy.ORCID 0000-0002-6755-285X
University of Padua · ITInstitute of Biophysics · BGUniversity of Trento · ITUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schwann cells are key players in neuro-regeneration: They sense "alarm" signals released by degenerating nerve terminals and differentiate toward a proregenerative phenotype, with phagocytosis of nerve debris and nerve guidance. At the murine neuromuscular junction, hydrogen peroxide (H

Indexed as

AnimalsAnnexin A2Cells, CulturedCytoskeletonGene Expression RegulationHydrogen PeroxideMice, Inbred C57BLNerve DegenerationProtein BiosynthesisRNASchwann CellsTranscriptomeAnnexin A2Hydrogen PeroxideRNAAnnexin A2axonal regenerationhydrogen peroxidelocal protein synthesislocal translationneuromuscular junctionnext-generation sequencingpolysome profilingRNA transportSchwann cellstranslatome

Identifiers

PMID29643068
PMCPMC6004060
OpenAlexW2798041607

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.