Evidence map›Paper›PMID 29657587›Full record

ReviewJournal of arrhythmia2018

Impact of ranolazine on ventricular arrhythmias - A systematic review.

George Bazoukis, Gary Tse, Konstantinos P Letsas, Costas Thomopoulos, Katerina K Naka, Panagiotis Korantzopoulos, Xenophon Bazoukis, Paschalia Michelongona, Stamatis S Papadatos, Konstantinos Vlachos and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of arrhythmia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Promising Therapies for Atrial Fibrillation and Ventricular Tachycardia.International journal of molecular sciences · 2022
    Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 5 countries.

George BazoukisDepartment of Cardiology Catheterization Laboratory Evangelismos General Hospital of Athens Athens Greece.ORCID 0000-0003-1009-9772
Gary TseDepartment of Medicine and Therapeutics Faculty of Medicine Chinese University of Hong Kong Hong Kong China.ORCID 0000-0001-5510-1253
Konstantinos P LetsasDepartment of Cardiology Catheterization Laboratory Evangelismos General Hospital of Athens Athens Greece.
Costas ThomopoulosDepartment of Cardiology Helena Venizelou Hospital Athens Greece.
Katerina K NakaSecond Department of Cardiology School of Medicine University of Ioannina Ioannina Greece.
Panagiotis KorantzopoulosFirst Department of Cardiology School of Medicine University of Ioannina Ioannina Greece.ORCID 0000-0002-4228-3593
Xenophon BazoukisDepartment of Cardiology General Hospital of Ioannina, "G Hatzikosta" Ioannina Greece.
Paschalia MichelongonaDepartment of Cardiology Catheterization Laboratory Evangelismos General Hospital of Athens Athens Greece.
Stamatis S PapadatosFaculty Department of Internal Medicine Athens School of Medicine Sotiria General Hospital National and Kapodistrian University of Athens Athens Greece.
Konstantinos VlachosDepartment of Cardiology Catheterization Laboratory Evangelismos General Hospital of Athens Athens Greece.
Tong LiuDepartment of Cardiology Tianjin Institute of Cardiology Second Hospital of Tianjin Medical University Tianjin China.
Michael EfremidisDepartment of Cardiology Catheterization Laboratory Evangelismos General Hospital of Athens Athens Greece.
Adrian BaranchukDivision of Cardiology, Electrophysiology and Pacing Kingston General Hospital Queen's University Kingston ON Canada.ORCID 0000-0002-3042-6569
Stavros StavrakisUniversity of Oklahoma Health Sciences Center Oklahoma City Oklahoma.
Costas TsioufisFirst Cardiology Clinic Hippokration Hospital University of Athens Athens Greece.
Evangelismos Hospital · GRNational and Kapodistrian University of Athens · GRUniversity of Ioannina · GRChinese University of Hong Kong · HKGeneral Hospital of Ioannina G. Hatzikosta · GRGeneral-Maternity District Hospital Helena Venizelou · GRQueen's University · CASecond Hospital of Tianjin Medical University · CNUniversity of Oklahoma Health Sciences Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ranolazine is a new medication for the treatment of refractory angina. However, except its anti-anginal properties, it has been found to act as an anti-arrhythmic. The aim of our systematic review is to present the existing data about the impact of ranolazine in ventricular arrhythmias. We searched MEDLINE and Cochrane databases as well clinicaltrials.gov until September 1, 2017 to find all studies (clinical trials, observational studies, case reports/series) reported data about the impact of ranolazine in ventricular arrhythmias. Our search revealed 14 studies (3 clinical trials, 2 observational studies, 8 case reports, 1 case series). These data reported a beneficial impact of ranolazine in ventricular tachycardia/fibrillation, premature ventricular beats, and ICD interventions in different clinical settings. The existing data highlight the anti-arrhythmic properties of ranolazine in ventricular arrhythmias.

Indexed as

anti‐arrhythmic drugsranolazineventricular arrhythmiasventricular fibrillationventricular tachycardia

Identifiers

PMID29657587
PMCPMC5891418
OpenAlexW2887697608

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.