Evidence map›Paper›PMID 29663153›Full record

ReviewCurrent obesity reports2018

Stress and Obesity: Are There More Susceptible Individuals?

Eline S van der Valk, Mesut Savas, Elisabeth F C van Rossum

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current obesity reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 159 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
159citing papers in PubMed, 7 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

159 citing papers in PubMed, 7 syntheses or guidelines pooled it, 392 citations in OpenAlex.

  1. Association of Adverse Childhood Experiences and Metabolic Syndrome: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  17. Childhood adversity and trajectories of health and quality of life in Australian children and adolescents: a latent class analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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99 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Eline S van der ValkObesity Center CGG, Erasmus MC, University Medical Center Rotterdam, Room D-428, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.
Mesut SavasObesity Center CGG, Erasmus MC, University Medical Center Rotterdam, Room D-428, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.
Elisabeth F C van RossumObesity Center CGG, Erasmus MC, University Medical Center Rotterdam, Room D-428, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands. e.vanrossum@erasmusmc.nl.
Erasmus University Rotterdam · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewStress has long been suspected to be interrelated to (abdominal) obesity. However, interindividual differences in this complex relationship exist. We suggest that the extent of glucocorticoid action partly explains these interindividual differences. We provide latest insights with respect to multiple types of stressors. RECENT

findingsIncreased long-term cortisol levels, as measured in scalp hair, are strongly related to abdominal obesity and to specific mental disorders. However, not all obese patients have elevated cortisol levels. Possibly, the interindividual variation in glucocorticoid sensitivity, which is partly genetically determined, may lead to higher vulnerability to mental or physical stressors. Other evidence for the important role for increased glucocorticoid action is provided by recent studies investigating associations between body composition and local and systemic corticosteroids. Stress may play a major role in the development and maintenance of obesity in individuals who have an increased glucocorticoid exposure or sensitivity. These insights may lead to more effective and individualized obesity treatment strategies.

Indexed as

Child Nutritional Physiological PhenomenaModels, PsychologicalAdultChildDisease SusceptibilityGenetic Predisposition to DiseaseGlucocorticoidsHumansHydrocortisoneHypothalamo-Hypophyseal SystemNerve Tissue ProteinsObesityPediatric ObesityPituitary-Adrenal SystemPolymorphism, GeneticReceptors, GlucocorticoidGlucocorticoidsHydrocortisoneNerve Tissue ProteinsReceptors, GlucocorticoidCorticosteroidsCortisolGlucocorticoid receptorGlucocorticoid receptor polymorphismsHair cortisolObesityStress

Identifiers

PMID29663153
PMCPMC5958156
OpenAlexW2800929313

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.