Evidence map›Paper›PMID 29670682›Full record

ArticleOxidative medicine and cellular longevity2018

Noninvasive Real-Time Characterization of Renal Clearance Kinetics in Diabetic Mice after Receiving Danshensu Treatment.

Lei Gao, Yiu-Wa Kwan, Andrew C Bulmer, Christopher W K Lai

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Lei GaoDepartment of Health Technology and Informatics, Hong Kong Polytechnic University, Kowloon, Hong Kong.
Yiu-Wa KwanSchool of Biomedical Sciences, Chinese University of Hong Kong, New Territories, Hong Kong.ORCID 0000-0002-9024-1275
Andrew C BulmerSchool of Medical Science and Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia.ORCID 0000-0002-2994-7893
Christopher W K LaiDepartment of Health Technology and Informatics, Hong Kong Polytechnic University, Kowloon, Hong Kong.ORCID 0000-0002-8010-7232
Hong Kong Polytechnic University · HKChinese University of Hong Kong · HKGriffith University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Danshensu (DSS) is an active ingredient extracted from the root of the Danshen that could ameliorate oxidative stress via upregulation of heme oxygenase- (HO-) 1. Little is known about the treatment effects of DSS on kidney function in diabetic mice. Therefore, the primary aim of the present study was to characterize the renal clearance kinetics of IRdye800CW in

Indexed as

Computer SystemsAnimalsBilirubinBiomarkersBlood GlucoseCreatinineDiabetes Mellitus, ExperimentalF2-IsoprostanesFastingHeme Oxygenase-1IndolesInsulinKidneyKineticsLactatesMice, Inbred C57BL3,4-dihydroxyphenyllactic acidBilirubinBiomarkersBlood GlucoseCreatinineF2-IsoprostanesHeme Oxygenase-1IndolesInsulinIRDye800Lactates

Identifiers

PMID29670682
PMCPMC5833022
OpenAlexW2793514794

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.