Evidence map›Paper›PMID 29693622›Full record

ReviewInternational journal of molecular sciences2018

Targeting Splicing in Prostate Cancer.

Effrosyni Antonopoulou, Michael Ladomery

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Role of alternative splicing events in endometrial cancer prognosis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Article
  9. Article
  10. Review
  11. Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  12. Article
  13. Alternative Acts: Oncogenic Splicing of Steroidogenic Enzymes in Prostate Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Effrosyni AntonopoulouFaculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Bristol BS16 1QY, UK. londinoantonopoulou@hotmail.com.
Michael LadomeryFaculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Bristol BS16 1QY, UK. Michael.Ladomery@uwe.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over 95% of human genes are alternatively spliced, expressing splice isoforms that often exhibit antagonistic functions. We describe genes whose alternative splicing has been linked to prostate cancer; namely

Indexed as

Alternative SplicingApoptosis Regulatory ProteinsGenetic TherapyHumansKruppel-Like Factor 6MaleProstatic NeoplasmsReceptors, AndrogenTranscriptional Regulator ERGVascular Endothelial Growth Factor AApoptosis Regulatory ProteinsBCL2L2 protein, humanERG protein, humanKLF6 protein, humanKruppel-Like Factor 6Receptors, AndrogenTranscriptional Regulator ERGVascular Endothelial Growth Factor AVEGFA protein, humanalternative splicingARBCL2L2ERGKLF6prostate cancerRNA interferencesplice factor kinasessplice factorssplice switching oligonucleotidesVEGFA

Identifiers

PMID29693622
PMCPMC5983716

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.