Evidence map›Paper›PMID 29700117›Full record

ArticleThe Journal of biological chemistry2018

Sterol carrier protein-2 deficiency attenuates diet-induced dyslipidemia and atherosclerosis in mice.

Hongliang He, Jing Wang, Paul J Yannie, Genta Kakiyama, William J Korzun, Shobha Ghosh

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hongliang HeFrom the Departments of Internal Medicine and.
Jing WangFrom the Departments of Internal Medicine and.
Paul J Yanniethe Hunter Homes McGuire Veterans Affairs Medical Center, Richmond, Virginia 23249.
Genta Kakiyamathe Hunter Homes McGuire Veterans Affairs Medical Center, Richmond, Virginia 23249.
William J KorzunClinical and Laboratory Sciences, Virginia Commonwealth University (VCU) Medical Center, Richmond, Virginia 23298 and.
Shobha GhoshFrom the Departments of Internal Medicine and shobha@vcu.edu.
University of Richmond · USHunter Holmes McGuire VA Medical Center · USVirginia Commonwealth University Medical Center · US

Funding

Hepatic Cholesteryl Ester Metabolism and Cholesterol EliminationR01HL097346 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI GHOSH, SHOBHA · 2010 to 2013
$1.5M
NHLBI NIH HHS R01 HL097346
6 · The paper itself

Abstract

Intracellular cholesterol transport proteins move cholesterol to different subcellular compartments and thereby regulate its final metabolic fate. In hepatocytes, for example, delivery of high-density lipoprotein (HDL)-associated cholesterol for bile acid synthesis or secretion into bile facilitates cholesterol elimination from the body (anti-atherogenic effect), whereas delivery for esterification and subsequent incorporation into apolipoprotein B-containing atherogenic lipoproteins (

Indexed as

AnimalsAtherosclerosisCarrier ProteinsCholesterolDiet, WesternDyslipidemiasFemaleGene DeletionIntestinal AbsorptionLipoproteins, VLDLLiverMaleMiceTriglyceridesCarrier ProteinsCholesterolLipoproteins, VLDLsterol carrier proteinsTriglyceridesanti-atherogenic effectatherosclerosiscardiovascular diseasecholesterol-binding proteincholesterol metabolismdietdyslipidemiahepatic VLDL secretionintracellular cholesterol transportsterol carrier protein

Identifiers

PMID29700117
PMCPMC6005425
OpenAlexW2801233784

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.