Evidence map›Paper›PMID 29704216›Full record

ArticlePsychopharmacology2018

Attentional capacities prior to drug exposure predict motivation to self-administer nicotine.

Youna Vandaele, Emilie Noe, Martine Cador, Françoise Dellu-Hagedorn, Stephanie Caille

Abstract read
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In one paragraph

Article in Psychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Youna VandaeleUniversité de Bordeaux, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, BP31, F-33076, Bordeaux, France.
Emilie NoeUniversité de Bordeaux, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, BP31, F-33076, Bordeaux, France.
Martine CadorUniversité de Bordeaux, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, BP31, F-33076, Bordeaux, France.
Françoise Dellu-HagedornUniversité de Bordeaux, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, BP31, F-33076, Bordeaux, France. francoise.dellu@u-bordeaux.fr.
Stephanie CailleUniversité de Bordeaux, Institut de Neurosciences Cognitives et Intégratives d'Aquitaine, BP31, F-33076, Bordeaux, France. stephanie.caille-garnier@u-bordeaux.fr.ORCID http://orcid.org/0000-0002-4906-3091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleNicotine can enhance attention and attribution of incentive salience to nicotine-associated stimuli. However, it is not clear whether inter-individual differences in attentional capacities prior to any exposure could play a role in vulnerability to nicotine self-administration. We further explored this vulnerability through pre-existing inter-individual differences in attention to a reward-predictive cue in drug-free animals.

methodsA cued version of the Fixed Consecutive Number schedule (FCN16

resultsOur results showed important inter-individual differences in response for nicotine during the progressive ratio schedule of reinforcement. By comparing rats in the lower and upper quartiles of the mean breaking point, we showed that high-motivated rats were also more sensitive to the reinforcing properties of nicotine than low-motivated ones. We found that while both groups did not differ in premature responding in the FCN16

conclusionsThese results suggest that higher attention to reward-associated cues prior to drug taking predicts vulnerability to nicotine-reinforcing properties.

Indexed as

CuesMotivationReinforcement, PsychologyAnimalsAttentionConditioning, OperantMaleNicotineNicotinic AgonistsRatsRewardSelf AdministrationNicotineNicotinic AgonistsAttentionCued fixed consecutive number scheduleInter-individual differencesIntravenous self-administrationNicotine addictionRat

Identifiers

PMID29704216

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.