Evidence map›Paper›PMID 29706799›Full record

ReviewMediators of inflammation2018

Recent Advances in the Molecular Mechanisms Underlying Pyroptosis in Sepsis.

Yu-Lei Gao, Jian-Hua Zhai, Yan-Fen Chai

Open access · goldAbstract readReview
In one paragraph

Review in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.

  1. Review: the role of GSDMD in sepsis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Cathelicidins Limit IntracellularPathogens (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Food science & nutrition · 2025
    Article
  11. Article
  12. Article
  13. The Protective Effect of Melatonin on LPS-Induced Myocardial InjuryCombinatorial chemistry & high throughput screening · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. TR4 worsen urosepsis by regulating GSDMD.European journal of medical research · 2024
    Article
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yu-Lei GaoDepartment of Emergency Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.ORCID 0000-0003-3099-2963
Jian-Hua ZhaiDepartment of Emergency Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.ORCID 0000-0002-7282-2981
Yan-Fen ChaiDepartment of Emergency Medicine, Tianjin Medical University General Hospital, Tianjin 300052, China.ORCID 0000-0002-1657-1284
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis is recognized as a life-threatening organ dysfunctional disease that is caused by dysregulated host responses to infection. Up to now, sepsis still remains a dominant cause of multiple organ dysfunction syndrome (MODS) and death among severe condition patients. Pyroptosis, originally named after the Greek words "

Indexed as

AnimalsHumansLipopolysaccharidesMultiple Organ FailureNeoplasm ProteinsPyroptosisSepsisLipopolysaccharidesNeoplasm Proteins

Identifiers

PMID29706799
PMCPMC5863298
OpenAlexW2792020729

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.