Evidence map›Paper›PMID 29739909›Full record

ArticlemBio2018

A High Frequency of HIV-Specific Circulating Follicular Helper T Cells Is Associated with Preserved Memory B Cell Responses in HIV Controllers.

M Claireaux, M Galperin, D Benati, A Nouël, M Mukhopadhyay, J Klingler, P de Truchis, D Zucman, S Hendou, F Boufassa and 3 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  15. TFrontiers in immunology · 2020
    Article
  16. Consensus Report on Shigella Controlled Human Infection Model: Immunological Assays.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

M ClaireauxPasteur Institute, Viral Pathogenesis Unit, Paris, France.
M GalperinPasteur Institute, Viral Pathogenesis Unit, Paris, France.
D BenatiPasteur Institute, Viral Pathogenesis Unit, Paris, France.
A NouëlPasteur Institute, Viral Pathogenesis Unit, Paris, France.
M MukhopadhyayPasteur Institute, Viral Pathogenesis Unit, Paris, France.
J KlinglerINSERM UMR_S1109, Center for Research in Immunology and Hematology, Medicine Faculty, Strasbourg Translational Medicine Federation (FMTS), Strasbourg University, Strasbourg, France.
P de TruchisAP-HP, Infectious and Tropical Diseases Department, Raymond Poincaré Hospital, Garches, France.
D ZucmanHIV Unit, Foch Hospital, Suresnes, France.
S HendouINSERM U1018, Center for Research in Epidemiology and Population Health (CESP), Le Kremlin-Bicêtre, France.
F BoufassaINSERM U1018, Center for Research in Epidemiology and Population Health (CESP), Le Kremlin-Bicêtre, France.
C MoogINSERM UMR_S1109, Center for Research in Immunology and Hematology, Medicine Faculty, Strasbourg Translational Medicine Federation (FMTS), Strasbourg University, Strasbourg, France.
O LambotteINSERM U1184, Center for Immunology of Viral Infections and Autoimmune Diseases, Le Kremlin-Bicêtre, France.
L A ChakrabartiPasteur Institute, Viral Pathogenesis Unit, Paris, France chakra@pasteur.fr.ORCID 0000-0002-1895-3630
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRHôpital Foch · FRUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follicular helper T cells (Tfh) play an essential role in the affinity maturation of the antibody response by providing help to B cells. To determine whether this CD4

Indexed as

B-LymphocytesCohort StudiesHIV-1HIV AntibodiesHIV InfectionsHumansT-Lymphocytes, Helper-InducerViral LoadHIV AntibodiesB lymphocytesHIV controllershuman immunodeficiency virusMHC-II tetramersT follicular helperT lymphocytes

Identifiers

PMID29739909
PMCPMC5941072
OpenAlexW2802866126

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.