Evidence map›Paper›PMID 29741413›Full record

ArticleBiodemography and social biology

Association Between Immigration History and Inflammatory Marker Profiles Among Older Adult Mexican Americans.

Chantel L Martin, Mary N Haan, Lindsay Fernandez-Rhodes, Anne Lee, Allison E Aiello

Erratum issuedAbstract read
In one paragraph

Article in Biodemography and social biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Chantel L Martina Department of Epidemiology, Gillings School of Global Public Health , University of North Carolina , Chapel Hill , NC , USA.
Mary N Haanb Department of Epidemiology and Biostatistics , University of California San Francisco , San Francisco , CA , USA.
Lindsay Fernandez-Rhodesa Department of Epidemiology, Gillings School of Global Public Health , University of North Carolina , Chapel Hill , NC , USA.
Anne Leeb Department of Epidemiology and Biostatistics , University of California San Francisco , San Francisco , CA , USA.
Allison E Aielloa Department of Epidemiology, Gillings School of Global Public Health , University of North Carolina , Chapel Hill , NC , USA.

Funding

Biostatstics for Research in Environmental HealthT32ES007018 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel, Rebecca Fry · 1985 to 2026
$31.3M
EPIDEMIOLOGY OF FUNCTIONAL STATUS IN ELDERLY HISPANICSR01AG012975 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HAAN, MARY N · 1997 to 2015
$13.8M
POPULATION STUDIEST32HD007168 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELIZABETH A FRANKENBERG · 1985 to 2026
$13.8M
Cardiovascular Epidemiology Training GrantT32HL007055 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wayne D. Rosamond · 1986 to 2026
$10.0M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Cancer Health Disparities Training ProgramT32CA128582 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ENG, EUGENIA, TATE, DEBORAH F. · 2009 to 2023
$3.4M
NCI NIH HHS T32 CA128582NHLBI NIH HHS T32 HL007055NIA NIH HHS R01 AG012975NICHD NIH HHS P2C HD050924NICHD NIH HHS T32 HD007168NIEHS NIH HHS T32 ES007018
6 · The paper itself

Abstract

Foreign-born Hispanics have better cardiometabolic health upon arrival in the US than their US-born counterparts, yet this advantage diminishes as duration of residence in the US increases. Underlying mechanisms explaining this paradox have been understudied. Using data from the Sacramento Area Latino Study on Aging (SALSA), this study examined immigration history (immigrant generation and duration of US residence) in relation to biomarkers of inflammation (interleukin-6 (IL-6), soluble forms of type 1 and 2 receptors of tumor necrosis factor-alpha (sTNF-R1 and sTNF-R2), C-reactive protein (CRP), leptin, adiponectin) in a sample of 1,290 predominantly Mexican-origin immigrants. Second and ≥3rd generation immigrants had higher IL-6 and leptin levels than 1st generation immigrants living in the US for less than 15 years (2nd generation percent difference = 45.9; 95% CI: 24.7, 70.7 and 3rd generation percent difference = 41.8; 95% CI: 17.7, 70.4). CRP and sTNF-R1 levels were higher among ≥3rd generation immigrants than 1st generation immigrants with less than 15 years of US residency. Worse inflammatory profiles were observed among Mexican-origin immigrants with longer US immigration histories, independent of health, and behavioral factors. Additional research is warranted to understand the factors that shape trajectories of biological risk across generations of Hispanics.

Indexed as

AgedAge FactorsBiomarkersC-Reactive ProteinEmigrants and ImmigrantsFemaleHumansInflammationInterleukin-6MaleMexican AmericansMiddle AgedProspective StudiesRisk FactorsTumor Necrosis Factor-alphaUnited StatesBiomarkersC-Reactive ProteinIL6 protein, humanInterleukin-6Tumor Necrosis Factor-alpha

Identifiers

PMID29741413
PMCPMC6075719

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.