Evidence map›Paper›PMID 29768415›Full record

ArticlePloS one2018

Automated and real-time segmentation of suspicious breast masses using convolutional neural network.

Viksit Kumar, Jeremy M Webb, Adriana Gregory, Max Denis, Duane D Meixner, Mahdi Bayat, Dana H Whaley, Mostafa Fatemi, Azra Alizad

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. A Review of Artificial Intelligence in Breast Imaging.Tomography (Ann Arbor, Mich.) · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Artificial intelligence in diagnostic ultrasonography.Diagnostic and interventional radiology (Ankara, Turkey) · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. EMT-NET: EFFICIENT MULTITASK NETWORK FOR COMPUTER-AIDED DIAGNOSIS OF BREAST CANCER.Proceedings. IEEE International Symposium on Biomedical Imaging · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Viksit KumarDepartment of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, United States of America.ORCID 0000-0003-0056-5223
Jeremy M WebbDepartment of Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, United States of America.
Adriana GregoryDepartment of Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, United States of America.
Max DenisDepartment of Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, United States of America.
Duane D MeixnerDepartment of Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, United States of America.
Mahdi BayatDepartment of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, United States of America.
Dana H WhaleyDepartment of Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, United States of America.
Mostafa FatemiDepartment of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, United States of America.
Azra AlizadDepartment of Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, United States of America.

Funding

Multi-parameter Nonlinear Elasticity Mapping of Breast MassesR01CA195527 · NCI · MAYO CLINIC ROCHESTER · PI ALIZAD, AZRA, FATEMI, MOSTAFA · 2016 to 2020
$2.8M
Classification of breast masses based on visco-elastic propertiesR01CA168575 · NCI · MAYO CLINIC ROCHESTER · PI FATEMI, MOSTAFA, INSANA, MICHAEL F · 2013 to 2018
$2.5M
Combined Acoustic Imaging and Viscoelastic Parameters Estimation in Breast CancerR01CA148994 · NCI · MAYO CLINIC ROCHESTER · PI ALIZAD, AZRA · 2011 to 2015
$2.4M
Generalized waveform methods for breast viscoelasticity mappingR01CA174723 · NCI · MAYO CLINIC ROCHESTER · PI FATEMI, MOSTAFA · 2014 to 2018
$1.8M
NCI NIH HHS R01 CA148994NCI NIH HHS R01 CA168575NCI NIH HHS R01 CA174723NCI NIH HHS R01 CA195527NIH HHS R01CA148994NIH HHS R01CA148994-S1NIH HHS R01CA168575NIH HHS R01CA174723NIH HHS R01CA195527
6 · The paper itself

Abstract

In this work, a computer-aided tool for detection was developed to segment breast masses from clinical ultrasound (US) scans. The underlying Multi U-net algorithm is based on convolutional neural networks. Under the Mayo Clinic Institutional Review Board protocol, a prospective study of the automatic segmentation of suspicious breast masses was performed. The cohort consisted of 258 female patients who were clinically identified with suspicious breast masses and underwent clinical US scan and breast biopsy. The computer-aided detection tool effectively segmented the breast masses, achieving a mean Dice coefficient of 0.82, a true positive fraction (TPF) of 0.84, and a false positive fraction (FPF) of 0.01. By avoiding positioning of an initial seed, the algorithm is able to segment images in real time (13-55 ms per image), and can have potential clinical applications. The algorithm is at par with a conventional seeded algorithm, which had a mean Dice coefficient of 0.84 and performs significantly better (P< 0.0001) than the original U-net algorithm.

Indexed as

Neural Networks, ComputerPattern Recognition, AutomatedAdultAgedAged, 80 and overAlgorithmsBreastBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularFemaleHumansImage Processing, Computer-AssistedMammographyMiddle Aged

Identifiers

PMID29768415
PMCPMC5955504

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.