Evidence map›Paper›PMID 29789368›Full record

ReviewmBio2018

The Case for an Expanded Concept of Trained Immunity.

Antonio Cassone

Open access · goldAbstract readReview
In one paragraph

Review in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. The theory of the inflammatory ecosystem.Science China. Life sciences · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. The Interplay betweenMicroorganisms · 2023
    Review
  9. Review
  10. Article
  11. Trained Immunity and Reactivity of Macrophages and Endothelial Cells.Arteriosclerosis, thrombosis, and vascular biology · 2021
    Review
  12. Article
  13. Article
  14. Review
  15. Pathogenesis and Clinical Relevance ofFrontiers in microbiology · 2020
    Review
  16. New Insights inFrontiers in cellular and infection microbiology · 2020
    Review
  17. Review
  18. Review
  19. A Role for Yeast/Pseudohyphal Cells ofFrontiers in microbiology · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Antonio CassonePolo della Genetica, Genomica e Biologia, University of Perugia, Perugia, Italy a.cassone@pologgb.com.
University of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trained immunity was originally proposed as a program of innate immunity memory by innate immunity cells of hematopoietic origin such as the monocytes/macrophages and the NK cells. Here I discuss some old and new data justifying this program and some specific, still unanswered, questions it raises regarding the model fungus

Indexed as

Adaptive ImmunityAnimalsCandida albicansCandidiasis, VulvovaginalCytokinesFemaleHumansImmunity, InnateKiller Cells, NaturalCytokinesCandidaimmunityinflammationinnate

Identifiers

PMID29789368
PMCPMC5964355
OpenAlexW2804832608

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.