Evidence map›Paper›PMID 29792201›Full record

ArticleParticle and fibre toxicology2018

Cerium dioxide nanoparticles exacerbate house dust mite induced type II airway inflammation.

Kirsty Meldrum, Sarah B Robertson, Isabella Römer, Tim Marczylo, Lareb S N Dean, Andrew Rogers, Timothy W Gant, Rachel Smith, Terry D Tetley, Martin O Leonard

Open access · goldAbstract read
In one paragraph

Article in Particle and fibre toxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Adverse effects and underlying mechanism of rare earth elements.Environmental health : a global access science source · 2025
    Pooled it
  2. Article
  3. Modulatory effects of CeOParticle and fibre toxicology · 2026
    Article
  4. Article
  5. Article
  6. Solute Carrier Family 26 Member 4 (SLC26A4), A Potential Therapeutic Target for Asthma.Journal of respiratory biology and translational medicine · 2024
    Article
  7. The MAK collection for occupational health and safety · 2024
    Review
  8. Article
  9. Review
  10. Glycosaminoglycan fromFood science & nutrition · 2021
    Article
  11. CD34+ derived macrophage and dendritic cells display differential responses to paraquat.Toxicology in vitro : an international journal published in association with BIBRA · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Kirsty MeldrumToxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK.
Sarah B RobertsonEnvironmental Hazards and Emergencies Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Harwell Campus, Chilton, OX110RQ, UK.
Isabella RömerToxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK.
Tim MarczyloToxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK.
Lareb S N DeanLung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK.
Andrew RogersLung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK.
Timothy W GantToxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK.
Rachel SmithToxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK.
Terry D TetleyLung Cell Biology, Airways Disease, National Heart & Lung Institute, Imperial College London, London, UK.
Martin O LeonardToxicology Department, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Chilton, OX110RQ, UK. Martin.Leonard@phe.gov.uk.
Imperial College London · GBKing's College London · GBNational Institute for Health Research · GBPublic Health England · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNanomaterial inhalation represents a potential hazard for respiratory conditions such as asthma. Cerium dioxide nanoparticles (CeO

resultsRepeated intranasal instillation of CeO

conclusionsCeO

Indexed as

Airway RemodelingAnimalsAsthmaCells, CulturedCeriumDisease Models, AnimalEpithelial CellsFemaleGene ExpressionHumansInhalation ExposureInterferon Regulatory Factor-3Interferon Type IMice, Inbred BALB CNanoparticlesPyroglyphidaeceric oxideCeriumInterferon Regulatory Factor-3Interferon Type IIrf3 protein, mouseAsthmaLungNanomaterialTranscriptomics

Identifiers

PMID29792201
PMCPMC5966909
OpenAlexW2806581632

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.