ArticleMolecular therapy : the journal of the American Society of Gene Therapy2018
Topical Lyophilized Targeted Lipid Nanoparticles in the Restoration of Skin Barrier Function following Burn Wound.
Open access · hybridAbstract read
In one paragraph
Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 65 citations in OpenAlex.
- Skin Transcriptome of Middle-Aged Women Supplemented With Natural Herbo-mineral Shilajit Shows Induction of Microvascular and Extracellular Matrix Mechanisms.Journal of the American College of Nutrition · 2019Trial
- Therapeutic Potential of Modulating Gene-MicroRNA Crosstalk in Burn Injury.International journal of molecular sciences · 2025Review
- Effects of Carbon-Based and Organic Nanoparticles in Advanced Dressings for Skin Regeneration: A Review.International wound journal · 2025Review
- Nanomanaging Chronic Wounds with Targeted Exosome Therapeutics.Pharmaceutics · 2025Review
- Tissue nanotransfection-based endothelial PLCγ2-targeted epigenetic gene editing rescues perfusion and diabetic ischemic wound healing.Molecular therapy : the journal of the American Society of Gene Therapy · 2025Article
- Nanotech meets antibiotics: nucleotide antibiotics delivered by lipid nanoparticles.Frontiers in cellular and infection microbiology · 2025Review
- Mitochondrial Bioenergetics of Functional Wound Closure is Dependent on Macrophage-Keratinocyte Exosomal Crosstalk.ACS nano · 2024Article
- Deficient functional wound closure as measured by elevated trans-epidermal water loss predicts chronic wound recurrence: An exploratory observational study.Scientific reports · 2024Observational
- Developing hydrogels for gene therapy and tissue engineering.Journal of nanobiotechnology · 2024Review
- Human Wound and Its Burden: Updated 2022 Compendium of Estimates.Advances in wound care · 2023Article
- Surface engineering of lipid nanoparticles: targeted nucleic acid delivery and beyond.Biophysics reports · 2023Article
- Bacterial Pyocyanin Inducible Keratin 6A Accelerates Closure of Epithelial Defect under Conditions of Mitochondrial Dysfunction.The Journal of investigative dermatology · 2023Article
- Nanoscopic and Functional Characterization of Keratinocyte-Originating Exosomes in the Wound Fluid of Non-Diabetic and Diabetic Chronic Wound Patients.Nano today · 2023Article
- Smart and versatile biomaterials for cutaneous wound healing.Biomaterials research · 2023Review
- Identification of a physiologic vasculogenic fibroblast state to achieve tissue repair.Nature communications · 2023Article
- Recent Progress of Lipid Nanoparticles-Based Lipophilic Drug Delivery: Focus on Surface Modifications.Pharmaceutics · 2023Review
- Driving adult tissue repair via re-engagement of a pathway required for fetal healing.Molecular therapy : the journal of the American Society of Gene Therapy · 2023Article
- Topical Delivery of ROS-Responsive Methotrexate Prodrug Nanoassemblies by a Dissolvable Microneedle Patch for Psoriasis Therapy.International journal of nanomedicine · 2023Article
- Transcriptomes reveal microRNAs and mRNAs in different photoperiods influencing cashmere growth in goat.PloS one · 2023Article
- Myogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss.NPJ Regenerative medicine · 2022Article
Corrections and comments
- Commented on by
Authors and funding
8 authors at 2 institutions in 2 countries.
Jilong LiDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA; Division of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Subhadip GhatakDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA; Center for Regenerative Medicine and Cell-Based Therapies, The Ohio State University, Columbus, OH 43210, USA.
Mohamed S El MasryDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA; Department of General Surgery (Plastic Surgery Unit), Zagazig University, 44519, Egypt.
Amitava DasDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA; Center for Regenerative Medicine and Cell-Based Therapies, The Ohio State University, Columbus, OH 43210, USA.
Yang LiuDivision of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Sashwati RoyDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA; Center for Regenerative Medicine and Cell-Based Therapies, The Ohio State University, Columbus, OH 43210, USA.
Robert J LeeDivision of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA; Center for Regenerative Medicine and Cell-Based Therapies, The Ohio State University, Columbus, OH 43210, USA.
Chandan K SenDepartment of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA; Center for Regenerative Medicine and Cell-Based Therapies, The Ohio State University, Columbus, OH 43210, USA. Electronic address: drchandanksen@gmail.com.
Lung Institute · USThe Ohio State University · US
Funding
Diabetic Foot Ulcer Clinical Research UnitU01DK119099 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Gayle M Gordillo, Sashwati Roy · 2018 to 2026
$5.4MWound Healing Endpoint and RecurrenceR01NR015676 · NINR · OHIO STATE UNIVERSITY · PI GORDILLO, GAYLE M, ROY, SASHWATI · 2015 to 2019
$2.6MRedox Control of Wound HealingR01GM069589 · NIGMS · OHIO STATE UNIVERSITY · PI SEN, CHANDAN K · 2004 to 2013
$2.3MTissue Oxygenation and Wound HealingR01GM077185 · NIGMS · OHIO STATE UNIVERSITY · PI SEN, CHANDAN K · 2007 to 2016
$2.3MBiofilms and Immunity in Chronic WoundsR01NR013898 · NINR · OHIO STATE UNIVERSITY · PI SEN, CHANDAN K, WOZNIAK, DANIEL J · 2012 to 2016
$2.1MMechanisms Underlying Impaired Diabetic Wound HealingR01DK114718 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI ROY, SASHWATI · 2018 to 2021
$1.6MMechanisms underlying impaired diabetic wound healingR01DK076566 · NIDDK · OHIO STATE UNIVERSITY · PI ROY, SASHWATI · 2008 to 2011
$1.2MMechanisms underlying impaired diabetic wound healingR56DK076566 · NIDDK · OHIO STATE UNIVERSITY · PI ROY, SASHWATI · 2016 to 2016
$347kNIDDK NIH HHS R01 DK076566NIDDK NIH HHS R01 DK114718NIDDK NIH HHS R56 DK076566NIDDK NIH HHS U01 DK119099NIGMS NIH HHS R01 GM069589NIGMS NIH HHS R01 GM077185NINR NIH HHS R01 NR013898NINR NIH HHS R01 NR015676
Abstract
Lyophilized keratinocyte-targeted nanocarriers (TLN
Indexed as
Freeze DryingAnimalsAntagomirsBurnsCell DifferentiationCell LineCell MovementCell ProliferationFilaggrin ProteinsFlow CytometryHumansKeratinocytesLipidsMaleMiceMicroRNAsAntagomirsFilaggrin ProteinsFLG protein, humanLipidsMicroRNAsburn wounddrug targetingmicroRNAsnanoparticleswound healing
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.